3-(1,1,1-TRIBUTYLSTANNYL)PYRIDINE CAS 59020-10-9

Introduction:Basic information about 3-(1,1,1-TRIBUTYLSTANNYL)PYRIDINE CAS 59020-10-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

3-(1,1,1-TRIBUTYLSTANNYL)PYRIDINE Basic information

Product Name:3-(1,1,1-TRIBUTYLSTANNYL)PYRIDINE
Synonyms:3-PYRIDYLTRI-n-BUTYLTIN 95%;3-Pyridyltributylstannane;3-Tris(but-1-ylstannyl)pyridine;3-(Tri-n-butylstannyl)pyridine, 97%;Pyridine,3-(tributylstannyl)-;3-(Tributylstannyl)pyridine 97%;tributyl(3-pyridyl)stannane;3-PYRIDYLTRI-N-BUTYLTIN
CAS:59020-10-9
MF:C17H31NSn
MW:368.14
EINECS:
Product Categories:Tributylstanny;Organostannes;Pyridine
Mol File:59020-10-9.mol

3-(1,1,1-TRIBUTYLSTANNYL)PYRIDINE Chemical Properties

Boiling point 132°C 0,3mm
density 1,15 g/cm3
Fp 110 °C
storage temp. -20°C
form liquid
pka5.21±0.12(Predicted)
Specific Gravity1.150
color Dark brown
Hydrolytic Sensitivity7: reacts slowly with moisture/water
Exposure limitsACGIH: TWA 0.1 mg/m3; STEL 0.2 mg/m3 (Skin)
NIOSH: IDLH 25 mg/m3; TWA 0.1 mg/m3

Safety Information

Hazard Codes T,Xi,N
Risk Statements 20/21/22-36/37/38-50/53-48/23/25-36/38-25-21
Safety Statements 26-36/37/39-61-60-45-35
RIDADR UN 2788 6.1/PG 3
WGK Germany 3
TSCA No
HazardClass 6.1
HazardClass IRRITANT, KEEP COLD, TOXIC
HS Code 29333990

3-(1,1,1-TRIBUTYLSTANNYL)PYRIDINE Usage And Synthesis

Uses3-Tributylstannylpyridine (CAS# 59020-10-9) can be used to prepare polyimide material that is resistant to atomic oxygen.
Synthesis

626-55-1

1461-22-9

59020-10-9

In a two-necked round-bottomed flask 0.5 mL (5.19 mmol) of 3-bromopyridine was dissolved in 25 mL of anhydrous ether and the reaction system was cooled to -78 °C. 3.89 mL (6.23 mmol) of n-butyllithium (1.6 M hexane solution) was slowly added dropwise and the reaction was stirred for 3 hours keeping the temperature at -78 °C. Subsequently, 1.55 mL (5.71 mmol) of tributyltin chloride was added and stirring was continued at -78°C for 30 minutes, then gradually warmed to room temperature and stirred for 12 hours. Upon completion of the reaction, the reaction was quenched by the addition of saturated aqueous ammonium chloride and extracted with ether. The organic layer was separated, dried with anhydrous magnesium sulfate and concentrated under reduced pressure to remove the solvent. Purification by column chromatography (eluent: hexane/ethyl acetate=9:1, v/v) afforded 1.58 g of the target product 3-(1,1,1-tributylmethylstannyl)pyridine as a clear oil (yield: 83%).

References[1] Patent: KR2015/142709, 2015, A. Location in patent: Paragraph 0441-0443
[2] Patent: US6498159, 2002, B1
[3] Patent: US6599917, 2003, B1
[4] Tetrahedron, 2013, vol. 69, # 2, p. 902 - 909
[5] Advanced Synthesis and Catalysis, 2017, vol. 359, # 5, p. 832 - 840

3-(1,1,1-TRIBUTYLSTANNYL)PYRIDINE Preparation Products And Raw materials

Raw materials3,5-Dibromopyridine-->3-Pyridyl bromide-->Tributyltin chloride-->Bis(tributyltin) oxide-->n-Butyllithium-->Hexane-->Diethyl ether
Preparation Products4-(PYRIDIN-3-YL)BENZALDEHYDE-->2,4(1H,3H)-Pyrimidinedione, 5-(3-pyridinyl)-
3-(((2R,3R,11bR)-2-hydroxy-3-isobutyl-10-methoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin
3-(1,2-DIMETHYL-3-INDOLYL)-3-[4-(DIETHYLAMINO)-2-METHYLPHENYL]PHTHALIDE CAS 36499-49-7
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