Introduction：Basic information about 3,4-Difluorophenylboronic acid CAS 168267-41-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
3,4-Difluorophenylboronic acid Basic information
| Product Name: | 3,4-Difluorophenylboronic acid |
| Synonyms: | 3,4-DIFLUOROBENZENE BORONIC ACID;3,4-DIFLUOROPHENYLBORONICACID;;3,4-Difluorophenylbo;3,4-Difluorophenylboronic acid, May contain varying amounts of anhydride, 97%;3,4-Difluorophenylboronic acid ,98%;3,4-Difluorophenylboronic acid,97%;dihydroxy(3,4-difluorophenyl)borane;3,4-DIFLUOROPHENYLBORONIC ACID FOR SYNTH;Boronic acid, B-(3,4-difluorophenyl)- |
| CAS: | 168267-41-2 |
| MF: | C6H5BF2O2 |
| MW: | 157.91 |
| EINECS: | 736-978-8 |
| Product Categories: | Boronic Acids;Boronic Acids;Boronic Acids and Derivatives;Substituted Boronic Acids;Boronic Acid;Aryl;Halogenated;Organoborons;HALIDE;blocks;BoronicAcids;FluoroCompounds;Fluorin-contained phenyl boronic acid series;Liquid crystal intermediates |
| Mol File: | 168267-41-2.mol |
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3,4-Difluorophenylboronic acid Chemical Properties
| Melting point | 305-310 °C (lit.) |
| Boiling point | 265.4±50.0 °C(Predicted) |
| density | 1.35±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | Powder |
| pka | 7.59±0.10(Predicted) |
| color | White |
| BRN | 7369788 |
| InChI | InChI=1S/C6H5BF2O2/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,10-11H |
| InChIKey | RMGYQBHKEWWTOY-UHFFFAOYSA-N |
| SMILES | B(C1=CC=C(F)C(F)=C1)(O)O |
| CAS DataBase Reference | 168267-41-2(CAS DataBase Reference) |
Safety Information
| Hazard Codes | Xn,Xi |
| Risk Statements | 36/37/38-22 |
| Safety Statements | 37/39-26-36 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| HS Code | 29319090 |
| Storage Class | 11 - Combustible Solids |
3,4-Difluorophenylboronic acid Usage And Synthesis
| Chemical Properties | white powder |
| Uses | suzuki reaction |
| Uses | 3,4-Difluorophenylboronic Acid is used as a building block in the synthesis of several organic compounds including that of substituted 6-phenylpurine bases and nucleosides via Suzuki-Miyaura cross-coupling reactions which show significant cytostatic activity in CCRF-CEM, HeLa, and L1210 cell lines. It is also used in the preparation of a potent cell penetrant Legumain inhibitor, 10t. |
| Uses | Intermediates of Liquid Crystals |
3,4-Difluorophenylboronic acid Preparation Products And Raw materials
| Preparation Products | (1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid-->3',4'-Difluoro-biphenyl-4-ol-->3',4'-DIFLUORO-BIPHENYL-4-CARBOXYLIC ACID-->3-BIPHENYL-3',4'-DIFLUORO-ACETIC ACID-->2-(3,4-Difluoro-phenoxy)acetonitrile-->4-(2,4-Difluorophenyl)-3-methyl-2(5H)-furanone |
