Introduction：Basic information about 3,5-Pyridinedicarboxylic acid CAS 499-81-0, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
3,5-Pyridinedicarboxylic acid Basic information
| Product Name: | 3,5-Pyridinedicarboxylic acid |
| Synonyms: | PYRIDINE-3,5-DICARBOXYLIC ACID;3,5-PyridinedicarboxylicAcidMin98%;3,5-Pyridinedicarboxylic Acid Min 98%;Pyridine-3,5-dicarboxylicacid,98%;AKOS 220-60;DINICOTINIC ACID;3,5-Pyridinedicarboxylate;5-Carboxynicotinic acid |
| CAS: | 499-81-0 |
| MF: | C7H5NO4 |
| MW: | 167.12 |
| EINECS: | 207-893-8 |
| Product Categories: | Building Blocks;C7;Aromatics;Chemical Synthesis;Heterocyclic Building Blocks;Pyridines;pyridine derivative;Acids and Derivatives;Heterocycles;Pyridine Series;Pyridine;Nicotine Derivatives;1 |
| Mol File: | 499-81-0.mol |
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3,5-Pyridinedicarboxylic acid Chemical Properties
| Melting point | >300 °C (lit.) |
| Boiling point | 295.67°C (rough estimate) |
| density | 1.5216 (rough estimate) |
| refractive index | 1.6280 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 1.0g/l |
| form | Powder |
| pka | 2.8(at 25℃) |
| color | White to almost white |
| Water Solubility | insoluble |
| BRN | 131640 |
| InChI | InChI=1S/C7H5NO4/c9-6(10)4-1-5(7(11)12)3-8-2-4/h1-3H,(H,9,10)(H,11,12) |
| InChIKey | MPFLRYZEEAQMLQ-UHFFFAOYSA-N |
| SMILES | C1=NC=C(C(O)=O)C=C1C(O)=O |
| CAS DataBase Reference | 499-81-0(CAS DataBase Reference) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38-20/21/22 |
| Safety Statements | 26-36-24/25-36/37/39 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 29333999 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
3,5-Pyridinedicarboxylic acid Usage And Synthesis
| Chemical Properties | White crystal powder |
| Uses | 3,5-Pyridinedicarboxylic Acid is a competitive inhibitor of butyrobetaine hydroxylase. It is also used as organic synthesis and pharmaceutical intermediates. |
| Definition | ChEBI: Dinicotinic acid is a pyridinedicarboxylic acid. It is a conjugate acid of a dinicotinate(1-). |
| Synthesis Reference(s) | Journal of Heterocyclic Chemistry, 4, p. 137, 1967 DOI: 10.1002/jhet.5570040127 |
3,5-Pyridinedicarboxylic acid Preparation Products And Raw materials
| Preparation Products | Nicardipine-->5-TERT-BUTOXYCARBONYLAMINO-PYRIDINE-3-CARBOXYLIC ACID-->Benidipine-->3,5-bis(chloromethyl)pyridine-->2,5-Pyridinedicarbonitrile(6CI,8CI,9CI)-->Nicotinic acid-->Methyl 5-aminopyridine-3-carboxylate-->potassiuM 5-(Methoxycarbonyl)nicotinate-->CIS-TERT-BUTYL 2,4-DIOXO-3-OXA-7-AZABICYCLO[3.3.1]NONANE-7-CARBOXYLATE-->(S)-N-Boc-piperidine-3-carboxylate methyl ester |
