3fluoro-3deoxyguanosine CAS 123402-21-1

Introduction：Basic information about 3fluoro-3deoxyguanosine CAS 123402-21-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

3fluoro-3deoxyguanosine Basic information

• Product Name: 3fluoro-3deoxyguanosine
• Synonyms: 2-AMino-9-(3-Deoxy-3-Fluoro-beta-D-Ribofuranosyl)-9H-Purin-6-Ol;3fluoro-3deoxyguanosine;9-[3-deoxy-3-C-fluoro--D-ribofuranosyl]guanine cas:;9-[3-Deoxy-3-C-fluoro-beta-D-ribofuranosyl]guanine;9-[3-DEOXY-3-C-FLUORO-SS-D-RIBOFURANOSYL]GUANINE;Aids001160;Aids-001160;2-amino-9-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
• CAS: 123402-21-1
• MF: C10H12FN5O4
• MW: 285.23
• Mol File: 123402-21-1.mol

3fluoro-3deoxyguanosine Chemical Properties

• Melting point: 289-291 °C
• density: 2.17±0.1 g/cm3(Predicted)
• storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• solubility: Acetonitrile: Slightly soluble DMSO: Soluble Methanol: Slightly soluble Water: Slightly soluble
• pka: 9?+-.0.20(Predicted)
• form: Solid
• InChI: InChI=1S/C10H12FN5O4/c11-4-3(1-17)20-9(6(4)18)16-2-13-5-7(16)14-10(12)15-8(5)19/h2-4,6,9,17-18H,1H2,(H3,12,14,15,19)/t3-,4-,6-,9-/m1/s1
• InChIKey: VDOWHLFGBWKXJC-DXTOWSMRSA-N
• SMILES: OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N)=O)N=C2)[C@H](O)[C@@H]1F

3fluoro-3deoxyguanosine Usage And Synthesis

Physical Form

Solid

Uses

3'-Deoxy-3'-fluoroguanosine is a useful research chemical.

References

[1] ANNE B. ELDRUP. Structure−Activity Relationship of Purine Ribonucleosides for Inhibition of Hepatitis C Virus RNA-Dependent RNA Polymerase[J]. Journal of Medicinal Chemistry, 2004, 47 9: 2283-2295. DOI: 10.1021/jm030424e

3fluoro-3deoxyguanosine Preparation Products And Raw materials

• Raw materials: α-D-Ribofuranoside, methyl 3-deoxy-3-fluoro-5-O-(phenylmethyl)-, 2-benzoate