3-Iodo-N-phenylcarbazole CAS 502161-03-7
3-Iodo-N-phenylcarbazole Basic information
| Product Name: | 3-Iodo-N-phenylcarbazole |
| Synonyms: | 3-Iodo-N-phenylcarbazole;3-Iodo-9-phenylcarbazole;3-iodo-9-phenyl-9H-carbazole;3-iodo-N-phenylcarbazol;3-Iodo-N-phenylcarba;3-iodo-9-phenylcarbazole,3-Iodo-9-phenylcarbazole;3-Iodo-9-phenylcarbazole/3-Iodo-N-phenylcarbazole;3- iodine-9- phenylcarbazole |
| CAS: | 502161-03-7 |
| MF: | C18H12IN |
| MW: | 369.2 |
| EINECS: | 808-151-1 |
| Product Categories: | OLED materials,pharm chemical,electronic;API intermediates |
| Mol File: | 502161-03-7.mol |
3-Iodo-N-phenylcarbazole Chemical Properties
| Melting point | 103.0 to 107.0 °C |
| Boiling point | 480.6±27.0 °C(Predicted) |
| density | 1.55±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | powder to crystal |
| color | White to Light yellow |
| CAS DataBase Reference | 502161-03-7 |
Safety Information
| HS Code | 2933998090 |
| Chemical Properties | White crystalline powder |
| Synthesis | 1150-62-5 502161-03-7 General procedure for the synthesis of 3-iodo-9-phenylcarbazole from N-phenylcarbazole: 2.433 g (10 mmol) of intermediate compound A (N-phenylcarbazole) was dissolved in 100 mL of 80% acetic acid solution, followed by the sequential addition of 1.357 g (5.35 mmol) of iodine monomers (I2) and 0.333 g (1.46 mmol) of o-n-octanoic acid ( H5IO6). The reaction mixture was stirred at 80 °C for 2 h under nitrogen protection. After completion of the reaction, the reaction mixture was extracted three times with ether (50 mL). The organic layers were combined and dried with anhydrous magnesium sulfate, followed by evaporation under reduced pressure to remove the solvent. The resulting crude product was purified by silica gel column chromatography to afford 3.23 g of intermediate compound B (3-iodo-9phenylcarbazole) as a white solid in 87% yield.1H NMR (CDCl3, 300 MHz) δ (ppm): 8.43 (d, 1H), 8.05 (d, 1H), 7.62 (dd, 1H), 7.61-7.75 (m, 2H) , 7.51-7.43 (m, 3H), 7.41-7.35 (m, 2H), 7.27 (dd, 1H), 7.14 (d, 1H). |
| References | [1] Patent: EP1661888, 2006, A1. Location in patent: Page/Page column 11 [2] Patent: US2008/174237, 2008, A1. Location in patent: Page/Page column 13-14 [3] Patent: EP2149555, 2010, A1. Location in patent: Page/Page column 19 [4] Patent: KR101791161, 2017, B1. Location in patent: Paragraph 0116; 0123-0128 [5] Patent: EP2738166, 2014, A1. Location in patent: Paragraph 0162 |
3-Iodo-N-phenylcarbazole Preparation Products And Raw materials
| Raw materials | N-PHENYLCARBAZOLE HYDROCHLORIDE-->Acetic acid-->Periodic acid-->iodine |
| Preparation Products | N-(4-(phenyl-9H-carbazol-3-yl)phenyl)biphenyl-4-aMine |
