Introduction：Basic information about 3-Methoxy-1-propanol CAS 1589-49-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
3-Methoxy-1-propanol Basic information
| Product Name: | 3-Methoxy-1-propanol |
| Synonyms: | 1-Hydroxy-3-methoxypropane;3-METHOXY-1-PROPANOL;3-METHOXYPROPAN-1-OL;3-METHOXYPROPANE-1-OL;3-METHOXYPROPANOL;3-IODO-2-FLUOROPYRIDINE;1-Methoxy-3-hydroxypropane;3-METHOXYPROPANOL-1 |
| CAS: | 1589-49-7 |
| MF: | C4H10O2 |
| MW: | 90.12 |
| EINECS: | 433-230-9 |
| Product Categories: | Alcohols;C2 to C6;Oxygen Compounds;Rabeprazole;PHARMACEUTICAL INTERMEDIATES |
| Mol File: | 1589-49-7.mol |
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3-Methoxy-1-propanol Chemical Properties
| Melting point | -84.2°C (estimate) |
| Boiling point | 150-152 °C |
| density | 0.942 g/mL at 20 °C (lit.) |
| refractive index | n20/D 1.413 |
| Fp | 38°C |
| storage temp. | Sealed in dry,Room Temperature |
| Water Solubility | Completely miscible in water |
| form | Liquid |
| pka | 14.89±0.10(Predicted) |
| color | Clear colorless |
| Specific Gravity | 0.942 |
| BRN | 1731204 |
| InChI | 1S/C4H10O2/c1-6-4-2-3-5/h5H,2-4H2,1H3 |
| InChIKey | JDFDHBSESGTDAL-UHFFFAOYSA-N |
| SMILES | COCCCO |
| LogP | -0.284 (est) |
| CAS DataBase Reference | 1589-49-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Trimethylene glycol monomethyl ether(1589-49-7) |
| EPA Substance Registry System | Trimethylene glycol monomethyl ether (1589-49-7) |
Safety Information
| Hazard Codes | Xi,F |
| Risk Statements | 10-38-36/38 |
| Safety Statements | 16-37-26 |
| RIDADR | UN 1987 3/PG 3 |
| WGK Germany | 1 |
| RTECS | UB7650000 |
| HazardClass | FLAMMABLE |
| PackingGroup | III |
| HS Code | 29094990 |
| Storage Class | 3 - Flammable liquids |
| Hazard Classifications | Flam. Liq. 3 |
3-Methoxy-1-propanol Usage And Synthesis
| Uses | 3-Methoxy-1-propanol can be used as an intermediate in organic synthesis and a pharmaceutical chemical reagent. It can be applied to the modification and derivatization of drug molecules and bioactive molecules. For example, 3-Methoxy-1-propanol can be used in the synthesis of the drug molecule rabeprazole. Rabeprazole is suitable for peptic ulcers, reflux esophagitis and Zollinger-Ellison syndrome. It has an inhibitory effect on both basal gastric acid and gastric acid secretion caused by stimulation. |
| Chemical Properties | Colorless liqui |
| Uses | 3-Methoxy-1-propanol is a primary alcohol. Kinetics of the reactions of 3-methoxy-1-propanol with phenyl isocyanate in the presence of metal catalysts has been reported. Selective synthesis of 3-methoxy-1-propanol from methanol and allyl alcohol with metal oxides and zeolites catalysts in the liquid phase has been studied. |
| General Description | 3-Methoxy-1-propanol is a primary alcohol. Kinetics of the reactions of 3-methoxy-1-propanol with phenyl isocyanate in the presence of metal catalysts has been reported. Selective synthesis of 3-methoxy-1-propanol from methanol and allyl alcohol with metal oxides and zeolites catalysts in the liquid phase has been studied. |
3-Methoxy-1-propanol Preparation Products And Raw materials
| Preparation Products | 2-Chloromethyl-3-methyl-4-(3-methoxypropoxy)pyridine hydrochloride-->1,3-Dimethoxypropane-->2-HYDROXYMETHYL-4-METHOXYPROPOXY-3-METHYLPYRIDINE-->(3-methoxy-propoxy)-acetic acid-->1-Iodo-3-methoxypropane |
