4,10-Aromadendranediol CAS 70051-38-6

Introduction：Basic information about 4,10-Aromadendranediol CAS 70051-38-6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

4,10-Aromadendranediol Basic information

• Product Name: 4,10-Aromadendranediol
• Synonyms: 4,10-Aromadendranediol;Aromadendrane-4β,10α-diol;10-Aromadendranediol;1H-Cycloprop[e]azulene-4,7-diol, decahydro-1,1,4,7-tetramethyl-, (1aR,4R,4aR,7S,7aS,7bR)-;10α-diol;Aromadendrane-4β
• CAS: 70051-38-6
• MF: C15H26O2
• MW: 238.37
• Mol File: 70051-38-6.mol

4,10-Aromadendranediol Usage And Synthesis

Uses

Aromadendrane-4β,10α-diol is a sesquiterpene alcohol. Aromadendrane-4β,10α-diol significantly ameliorates the Aβ1-42 peptide-induced memory impairment. Aromadendrane-4β,10α-diol can be used for Alzheimer's disease (AD) research[1].

in vivo

Aromadendrane-4β,10α-diol (1 μg/mouse, i.c.v.) significantly increases the activity of antioxidant enzymes (glutathione, GSH) and decreases of lipid peroxidation in Aβ1-42 (400 pmol/mouse, i.c.v.) mice^[1].

References

[1] Amoah SK, et al. Inhibitory effect of sesquiterpene lactones and the sesquiterpene alcohol aromadendrane-4β,10α-diol on memory impairment in a mouse model of Alzheimer. Eur J Pharmacol. 2015 Dec 15;769:195-202. DOI:10.1016/j.ejphar.2015.11.018