4,4'-Methylene bis(2-chloroaniline) CAS 101-14-4
Introduction：Basic information about 4,4'-Methylene bis(2-chloroaniline) CAS 101-14-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
4,4'-Methylene bis(2-chloroaniline) Basic information
| Product Name: | 4,4'-Methylene bis(2-chloroaniline) |
| Synonyms: | METHYLENEBIS(2-CHLOROANILINE);CHEMBRDG-BB 5180272;3,3’-Dichloro-4,4’-diaminodiph;3,3’-dicloro-4,4’-diaminodifenilmetano;3,3'-Dichlor-4,4'-diaminodiphenylmethan;3,3'-Dichloro-4,4'-diaminodifenilmetano;3,3'-Dicloro-4,4'-diaminodifenilmetano;4-(4-Amino-3-chlorobenzyl)-2-chlorophenylamine |
| CAS: | 101-14-4 |
| MF: | C13H12Cl2N2 |
| MW: | 267.15 |
| EINECS: | 202-918-9 |
| Product Categories: | Vulcanizer;Diphenylmethanes (for High-Performance Polymer Research);Functional Materials;Reagent for High-Performance Polymer Research;Organics |
| Mol File: | 101-14-4.mol |
4,4'-Methylene bis(2-chloroaniline) Chemical Properties
| Melting point | 102-107 °C(lit.) |
| Boiling point | 202-214 °C0.3 mm Hg(lit.) |
| density | 1.44 |
| vapor pressure | 0.001Pa at 20℃ |
| refractive index | 1.6710 (estimate) |
| Fp | >230 °F |
| solubility | Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | solid |
| pka | 3.33±0.25(Predicted) |
| color | Light orange to Yellow to Green |
| Water Solubility | <0.1 g/100 mL at 25 ºC |
| Merck | 14,6059 |
| BRN | 1882318 |
| Stability: | Stable, but decomposes exothermically, and possibly explosively, above 200 C. Incompatible with strong oxidizing agents. |
| Major Application | environmental |
| InChI | 1S/C13H12Cl2N2/c14-10-6-8(1-3-12(10)16)5-9-2-4-13(17)11(15)7-9/h1-4,6-7H,5,16-17H2 |
| InChIKey | IBOFVQJTBBUKMU-UHFFFAOYSA-N |
| SMILES | Nc1ccc(Cc2ccc(N)c(Cl)c2)cc1Cl |
| LogP | 2.5 at 25℃ |
| CAS DataBase Reference | 101-14-4(CAS DataBase Reference) |
| IARC | 1 (Vol. Sup 7, 57, 99, 100F) 2012 |
| NIST Chemistry Reference | Aniline), methylene bis-4,4'-(2-chloro-(101-14-4) |
| EPA Substance Registry System | 4,4'-Methylenebis(2-chloroaniline) (101-14-4) |
Safety Information
| Hazard Codes | T,N |
| Risk Statements | 45-22-50/53-53-50-68 |
| Safety Statements | 53-45-60-61-36/37 |
| RIDADR | UN 3077 9/PG 3 |
| OEB | E |
| OEL | TWA: 0.003 mg/m3 [skin] |
| WGK Germany | 3 |
| RTECS | CY1050000 |
| TSCA | TSCA listed |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 29215900 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 1 Carc. 1B Muta. 2 |
| Hazardous Substances Data | 101-14-4(Hazardous Substances Data) |
| Toxicity | LD50 oral in rat: 1140mg/kg |
| Description | 4,4'-Methylene bis(2-chloroaniline) (or MBOCA) is a synthetic chemical used primarily to make polyurethane products. Pure MBOCA is a colorless, crystalline solid, but the commonly used form is usually yellow, tan, or brown pellets. It has no smell or taste. Examples of these products include gears, gaskets, sport boots, roller skate wheels, shoe soles, rolls and belt drives in cameras, computers and copy machines, wheels and pulleys for escalators and elevators, components in home appliances, and various military applications. It is also used as a coating in chemical reactions to "set" glues, plastics, and adhesives. Because plastics have many uses, MBOCA is widely used. |
| Chemical Properties | off-white powder |
| Uses | Curing agent for polyurethanes andepoxy resins |
| Uses | MOCA (4,4'-Methylene bis(2-chloroaniline)) is widely used in machinery, automobile, aircraft manufacturing, mining, industrial and sports facilities (such as plastic track and plastic floor) can be used for curing and waterproof coatings such as epoxy resin, which can be given to polyester and polyether elastomer most good physical and mechanical properties and the results. |
| Production Methods | The production of MOCA (4,4'-Methylene bis(2-chloroaniline)) in the United States has ceasedsince 1979 and is now imported, mainly from Japan. Morethan 1.9 million lb was imported in 1989. The compound iscurrently used as a curing agent for isocyanate-containingpolymers and in the manufacture of polyurethane foams,epoxy resins, gun mounts, jet engine turbine blades, radarsystems, and components in home appliances. It is also amodel compound for studying carcinogenesis. |
| Definition | ChEBI: A chloroaniline that consists of two 2-chloroaniline units joined by a methylene bridge. |
| General Description | Tan-colored pellets or an off-white solid. Slight odor. |
| Air & Water Reactions | Insoluble in water. |
| Reactivity Profile | 4,4'-Methylene bis(2-chloroaniline) is a weak base. Undergoes an exothermic and self-sustaining decomposition reaction when exposed to heat above 392°F, In a closed container, the pressure buildup can be rapid enough to cause an explosion. |
| Hazard | Toxic. A confirmed carcinogen, absorbedby skin. Causes bladder cancer and methe-moglobinemia. |
| Health Hazard | 4,4￠-Methylene bis(2-chloroaniline),or MOCA, is carcinogenic in experimentalanimals. |
| Fire Hazard | Flash point data for 4,4'-Methylene bis(2-chloroaniline) are not available. 4,4'-Methylene bis(2-chloroaniline) is probably combustible. |
| Flammability and Explosibility | Non flammable |
| Safety Profile | Confirmed carcinogenwith experimental carcinogenic andtumorigenic data. Poison by ingestion andintraperitoneal routes. Mutation datareported. Flammable liquid. Reactive withactive metals such as sodium, potassium,magnesium, or zinc. When heated todecomposition it emits very toxic fumes ofCland NOx. |
| Carcinogenicity | 4,4′-Methylenebis(2-chloroaniline) is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals. |
4,4'-Methylene bis(2-chloroaniline) Preparation Products And Raw materials
| Raw materials | Formaldehyde-->2-Chloroaniline |
