Introduction：Basic information about 4,5-Dicyanoimidazole CAS 1122-28-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
4,5-Dicyanoimidazole Basic information
| Product Name: | 4,5-Dicyanoimidazole |
| Synonyms: | AURORA 15196;IMIDAZOLE-4,5-DICARBONITRILE;DCI;1h-imidazole-4,5-dicarbonitrile;4,5-DICYANOIMIDAZOLE;4,5-IMIDAZOLEDICARBONITRILE;4,5-two -iMidazole;ACTIVATOR |
| CAS: | 1122-28-7 |
| MF: | C5H2N4 |
| MW: | 118.1 |
| EINECS: | 214-344-6 |
| Product Categories: | Dicyanopyrazines, etc. (Building Blocks for Phthalonitriles & Naphthalonitriles);Functional Materials;Phthalonitriles & Naphthalonitriles;Naphthyridine,Quinoline;Imidaxoles;Imidazol&Benzimidazole;Coupling Reagent;blocks;Carboxes;Imidazoles;Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines;Pyridines ,Halogenated Heterocycles;1 |
| Mol File: | 1122-28-7.mol |
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4,5-Dicyanoimidazole Chemical Properties
| Melting point | 168-175 °C(lit.) |
| Boiling point | 569.3±35.0 °C(Predicted) |
| density | 0.791 g/mL at 25 °C |
| Fp | 50 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Soluble in Acetonitrile: 1.8g/10ml, DMSO, Methanol. |
| pka | 5.01±0.10(Predicted) |
| form | Crystalline Powder |
| color | solid white |
| BRN | 118208 |
| InChI | InChI=1S/C5H2N4/c6-1-4-5(2-7)9-3-8-4/h3H,(H,8,9) |
| InChIKey | XGDRLCRGKUCBQL-UHFFFAOYSA-N |
| SMILES | C1NC(C#N)=C(C#N)N=1 |
| CAS DataBase Reference | 1122-28-7(CAS DataBase Reference) |
Safety Information
| Hazard Codes | Xi,Xn,F |
| Risk Statements | 37/38-41-36/37/38-20/22-36-20/21/22-11 |
| Safety Statements | 26-39-36/37/39-36/37-16 |
| RIDADR | UN 1648 3/PG 2 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29332900 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Dam. 1
Skin Irrit. 2
STOT SE 3 |
4,5-Dicyanoimidazole Usage And Synthesis
| Chemical Properties | white crystalline powder |
| Uses | 4,5-Dicyanoimidazole is used in activation of nucleoside phosphoramidites during solid-phase oligonucleotide synthesis, and synthesis of nucleoside phosphoramidites, synthesis of novel nucleosides. It is often used as an alternative to tetrazole. |
| Synthesis Reference(s) | Synthesis, p. 767, 1988 DOI: 10.1055/s-1988-27702 |
| General Description | 4,5-Dicyanoimidazole (DCI) participates as an activator in the synthesis of oligonucleotides. |
4,5-Dicyanoimidazole Preparation Products And Raw materials
| Raw materials | Triethyl orthoformate-->Anisole-->Diaminomaleonitrile-->Temozolomide Impurity 16-->2,3-DIAMINOBUT-2-ENEDINITRILE-->5-Amino-1H-imidazol-4-carbonitrile |
| Preparation Products | 4,5-Imidazoledicarboxylic acid-->2-BROMO-1H-IMIDAZOLE-4,5-DICARBONITRILE-->1H-Imidazole-4,5-dicarbonitrile, 1-ethyl- |
