Introduction：Basic information about 4-[(3S)-1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol CAS 17676-24-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
4-[(3S)-1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol Basic information
| Product Name: | 4-[(3S)-1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol |
| Synonyms: | 4-[(3S)-1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol;hinokiresinol;4,4'-[(E)-3-Vinyl-1-propene-1,3-diyl]bis[phenol];4-[1-[(E)-4-Hydroxystyryl]allyl]phenol;C10628;cis-Hinokiresinol;trans-Hikiresil;trans-Hinokiresinol |
| CAS: | 17676-24-3 |
| MF: | C17H16O2 |
| MW: | 252.31 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 17676-24-3.mol |
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4-[(3S)-1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol Chemical Properties
| Melting point | 69-71 °C(Solv: chloroform (67-66-3)) |
| Boiling point | 429.4±40.0 °C(Predicted) |
| density | 1.163±0.06 g/cm3(Predicted) |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
| pka | 9.88±0.26(Predicted) |
| color | Yellow to orange |
| LogP | 3.710 (est) |
Safety Information
4-[(3S)-1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol Usage And Synthesis
| Description | Hinokiresinol (trans-hinokiresinol) and nyasol (cis-hinokiresinol) possess appreciable estrogen receptor binding activity, they can stimulate the proliferation of estrogen-dependent T47D breast cancer cells, and their stimulatory effects could be blocked by an estrogen antagonist, indicating that they are estrogen agonists. trans- and cis-Hinokiresinols have similar free radical scavenging and anti-inflammatory activities, they also have anti-ischemic effects, only trans-hinokiresinol can significantly decrease neuronal injury in cultured cortical neurons exposed to oxygen-glucose deprivation followed by re-oxygenation. 3. Hinokiresinol is a novel inhibitor of LTB4 binding to the human neutrophils. 4. Hinokiresinol has antiallergic effect, it inhibits IgE-induced mouse passive cutaneous anaphylaxis reaction. |
| Uses | (-)-Hinokiresinol (Hinokiresinol; trans-Hinokiresinol) can be isolated from Chamaecyparis obtusa. (-)-Hinokiresinol has weak termiticidal activity but strong antifeedant and repellent activity[1]. |
| Definition | ChEBI: (-)-hinokiresinol is a 1,3-bis(p-hydroxyphenyl)pentane-1,4-diene that has 1E,3S configuration. A natural product found in Chamaecyparis obtusa. It has a role as a metabolite. It is a norlignan and a 1,3-bis(p-hydroxyphenyl)pentane-1,4-diene. |
| target | Estrogen receptor | NOS | IL Receptor | TNF-α | Progestogen receptor |
| References | [1] Morikawa T, et al. Antitermitic activity of extracts from Chamaecyparis obtusa branch heartwood[J]. European Journal of Wood and Wood Products, 2014, 72: 651-657. |
4-[(3S)-1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol Preparation Products And Raw materials
