4-Bromo-1-butene CAS 5162-44-7

Introduction：Basic information about 4-Bromo-1-butene CAS 5162-44-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

4-Bromo-1-butene Basic information

• Product Name: 4-Bromo-1-butene
• Synonyms: 1-Bromo-3-butene;1-butene,4-bromo-;3-BUTENYL BROMIDE;4-BROMO-1-BUTENE, STAB.;4-Bromo-1-butene, 98+%;4-Bromo-1-butene, GC 98%;4-bromo-1-buten;4-bromo-but-1-ene
• CAS: 5162-44-7
• MF: C4H7Br
• MW: 135
• EINECS: 225-937-4
• Product Categories: Building Blocks;Chemical Synthesis;Halogenated Hydrocarbons;Organic Building Blocks;omega-Functional Alkanols, Carboxylic Acids, Amines & Halides;omega-Unsaturated Halides;Alkenyl;Halogenated Hydrocarbons;Organic Building Blocks;Halides;bc0001
• Mol File: 5162-44-7.mol

4-Bromo-1-butene Chemical Properties

• Melting point: -115.07°C (estimate)
• Boiling point: 98-100 °C (lit.)
• density: 1.33 g/mL at 25 °C (lit.)
• refractive index: n20/D 1.462(lit.)
• Fp: 49 °F
• storage temp.: Store below +30°C.
• solubility: 0.76g/l
• form: Liquid
• color: Clear colorless to light brownish
• Specific Gravity: 1.330
• Water Solubility: Miscible with water, benzene, ether and ethanol.
• Sensitive: Light Sensitive
• BRN: 1098377
• Stability: Stable. Incompatible with strong bases, strong oxidizing agents. Highly flammable. Light sensitive.
• InChI: 1S/C4H7Br/c1-2-3-4-5/h2H,1,3-4H2
• InChIKey: DMAYBPBPEUFIHJ-UHFFFAOYSA-N
• SMILES: BrCCC=C
• CAS DataBase Reference: 5162-44-7(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Butene, 4-bromo-(5162-44-7)
• EPA Substance Registry System: 1-Butene, 4-bromo- (5162-44-7)

Safety Information

• Hazard Codes: F,Xn,Xi
• Risk Statements: 11-36/37-42/43
• Safety Statements: 26-36/37/39
• RIDADR: UN 1993 3/PG 2
• WGK Germany: 3
• F: 8-19
• TSCA: TSCA listed
• HazardClass: 3
• PackingGroup: II
• HS Code: 29033036
• Storage Class: 3 - Flammable liquids
• Hazard Classifications: Eye Irrit. 2 Flam. Liq. 2 Resp. Sens. 1 Skin Sens. 1 STOT SE 3

4-Bromo-1-butene Usage And Synthesis

Chemical Properties

colourless liquid

Uses

4-Bromo-1-butene is a brominated alkene used as a reagent in organic synthesis.

Uses

4-Bromo-1-butene is used in the preparation of 4-(3-butenyloxy)benzoic acid and largazole. It is also used in double alkylation of lactams followed by Grubbs ring-closing metathesis to yield gymnodimine. Further, it serves as a reagent in the preparation of dienehydrazides.

Synthesis Reference(s)

Tetrahedron Letters, 25, p. 251, 1984 DOI: 10.1016/S0040-4039(00)99853-8

General Description

Stereoselective epoxidation of 4-bromo-1-butene was carried out with three alkene-utilizing bacteria: Mycobacterium LI, Mycobacterium E3 and Nocardia IP1.

4-Bromo-1-butene Preparation Products And Raw materials

• Raw materials: 2,6-Piperidinedione, 3,3-dimethyl--->methylcyclopropane-->Cyclobutyl bromide-->1,3-Dibromobutane-->Cylopropylmethyl chloride
• Preparation Products: Diethyl 1,1-cyclobutanedicarboxylate-->1,7-Octadiene-->7-Bromoheptanenitrile-->4-bromobutyraldehyde-->4-bromobutan-2-one-->5-Hexenoic acid, 2,2-dimethyl-, methyl ester-->Benzoic acid, 4-(4-penten-1-yl)--->1H-Indole, 1-(3-buten-1-yl)-