5,7-DIHYDROXY-3',4',5'-TRIMETHOXYFLAVONE CAS 18103-42-9

Introduction：Basic information about 5,7-DIHYDROXY-3',4',5'-TRIMETHOXYFLAVONE CAS 18103-42-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

5,7-DIHYDROXY-3',4',5'-TRIMETHOXYFLAVONE Basic information

• Product Name: 5,7-DIHYDROXY-3',4',5'-TRIMETHOXYFLAVONE
• Synonyms: TRICIN METHYL ETHER;TRICIN-4'-METHYL ETHER;DIHYDROXY-3',4',5'-TRIMETHOXYFLAVONE, 5,7-;5,7-DIHYDROXY-3'',4'',5''-TRIMETHOXYFLAVONE WITH HPLC;5,7-dihydroxy-2-(3,4,5-trimethoxyphenyl)-4-benzopyrone;5,7-Dihydroxy-3',4',5'-trimethoxy;NSC 123410;3',4',5'-O-trimethyltricetin
• CAS: 18103-42-9
• MF: C18H16O7
• MW: 344.32
• EINECS: 242-001-0
• Product Categories: Penta-substituted Flavones
• Mol File: 18103-42-9.mol

5,7-DIHYDROXY-3',4',5'-TRIMETHOXYFLAVONE Chemical Properties

• Melting point: 266-276°C
• Boiling point: 562.4±50.0 °C(Predicted)
• density: 1.387±0.06 g/cm3(Predicted)
• pka: 6.47±0.40(Predicted)

5,7-DIHYDROXY-3',4',5'-TRIMETHOXYFLAVONE Usage And Synthesis

Uses

Tricetin 3',4',5'-trimethyl ether (5,7-Dihydroxy-3',4',5'-trimethoxyflavone) is a flavone glucoside, that can be isolated the flowers of Chrysanthemum sinensea. Tricetin 3',4',5'-trimethyl ether displays xanthine oxidase competitive-type inhibitory activity, with an IC50 of 0.51 μM and a Ki of 0.37 μM[1].

Definition

ChEBI: A trimethoxyflavone that is the 3',4',5'-tri-O-methyl ether of tricetin.

References

[1] Nguyen MT, Awale S, Tezuka Y, Ueda JY, Tran Ql, Kadota S. Xanthine oxidase inhibitors from the flowers of Chrysanthemum sinense. Planta Med. 2006 Jan;72(1):46-51. DOI:10.1055/s-2005-873181