Introduction：Basic information about 5-Amino-3-phenyl-1,2,4-thiadiazole CAS 17467-15-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
5-Amino-3-phenyl-1,2,4-thiadiazole Basic information
| Product Name: | 5-Amino-3-phenyl-1,2,4-thiadiazole |
| Synonyms: | 2-methyl-2-oxolanamine;NSC 119930;3-phenyl-1,2,4-thiadiazol-5-ylamine;3-Phenyl-1,2,4-triazol-5-ylamine;5-AMINO-3-PHENYL-1,2,4-THIADIAZOLE 99%;5-Amino-3-phenyl-1,2,4-thiadiazole,99%;5-AMino-3-phenyl-1,2,4-thiadiazole, 99% 5GR;3-Phenyl-1,2,4-thiadiazol-5-aMine, >95% |
| CAS: | 17467-15-1 |
| MF: | C8H7N3S |
| MW: | 177.23 |
| EINECS: | 241-485-0 |
| Product Categories: | |
| Mol File: | 17467-15-1.mol |
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5-Amino-3-phenyl-1,2,4-thiadiazole Chemical Properties
| Melting point | 152-156 °C |
| density | 1.2353 (rough estimate) |
| refractive index | 1.5700 (estimate) |
| storage temp. | 2-8°C |
| form | powder |
| color | White |
| InChI | InChI=1S/C8H7N3S/c9-8-10-7(11-12-8)6-4-2-1-3-5-6/h1-5H,(H2,9,10,11) |
| InChIKey | OYAHSBDYBOBAAQ-UHFFFAOYSA-N |
| SMILES | S1C(N)=NC(C2=CC=CC=C2)=N1 |
| CAS DataBase Reference | 17467-15-1(CAS DataBase Reference) |
| EPA Substance Registry System | 1,2,4-Thiadiazol-5-amine, 3-phenyl- (17467-15-1) |
Safety Information
| Hazard Codes | Xn,Xi |
| Risk Statements | 36/37/38-20/21/22-41-22 |
| Safety Statements | 36/37/39-26-22 |
| TSCA | TSCA listed |
| HazardClass | IRRITANT |
| HS Code | 29341000 |
5-Amino-3-phenyl-1,2,4-thiadiazole Usage And Synthesis
| Description | 5-Amino-3-phenyl-1,2,4-thiadiazole is an important organic synthetic reagent with remarkable reactivity and stability and has been used in the synthesis of a variety of heterocyclic compounds including 1,2,4-triazol-3-ylphenyls, derivatives of 2-aryl-5-amino-thiadiazole, 5-amino-1,2,4-thiadiazol-3-phenyls, and 5 -amino-1,2,4-thiadiazole-3-phenyl-3-methyl derivatives. It is also used in the synthesis of polymers such as poly(5-amino-3-phenyl-1,2,4-thiadiazole). In addition, 5-amino-3-phenyl-1,2,4-thiadiazole is an inhibitor of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX). The compound inhibits the release of pro-inflammatory cytokines such as tumour necrosis factor-α (TNF-α) and interleukin-1β (IL-1β). |
| Chemical Properties | LIGHT BROWNISH FINE CRYSTALLINE POWDER |
| Uses | 3-Phenyl-1,2,4-thiadiazol-5-amine is used as a reactant in the preparation of thiazole and thiadiazole derivatives as potent and selective human adenosine A3 receptor antagonists. |
5-Amino-3-phenyl-1,2,4-thiadiazole Preparation Products And Raw materials
