Introduction：Basic information about 5-AMINOVALERIC ACID CAS 660-88-8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
5-AMINOVALERIC ACID Basic information
| Product Name: | 5-AMINOVALERIC ACID |
| Synonyms: | 5-Aminovaleric acid≥ 98% (HPLC);5-Ava-OH;H2N(CH2)4COOH;5-AMinovaleric acid, 97% 5GR;Pentanoic acid, 5-amino-;Valeric acid, 5-amino-;DELTA-AMINOVALERIC ACID;DELTA-AMINO-N-VALERIC ACID |
| CAS: | 660-88-8 |
| MF: | C5H11NO2 |
| MW: | 117.15 |
| EINECS: | 211-544-5 |
| Product Categories: | omega-Aminocarboxylic Acids;omega-Functional Alkanols, Carboxylic Acids, Amines & Halides;Amino Acids and Derivatives;Miscellaneous |
| Mol File: | 660-88-8.mol |
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5-AMINOVALERIC ACID Chemical Properties
| Melting point | 158-161 °C(lit.) |
| Boiling point | 247.5±23.0 °C(Predicted) |
| density | 1.2000 (estimate) |
| refractive index | 1.4650 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly), Water (Slightly) |
| pka | 4.27(at 25℃) |
| form | Crystalline Powder |
| color | White to off-white |
| BRN | 906833 |
| Major Application | peptide synthesis |
| InChI | InChI=1S/C5H11NO2/c6-4-2-1-3-5(7)8/h1-4,6H2,(H,7,8) |
| InChIKey | JJMDCOVWQOJGCB-UHFFFAOYSA-N |
| SMILES | C(O)(=O)CCCCN |
| CAS DataBase Reference | 660-88-8(CAS DataBase Reference) |
Safety Information
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 22-24/25-36-26 |
| WGK Germany | 3 |
| HS Code | 29224999 |
| Storage Class | 11 - Combustible Solids |
5-AMINOVALERIC ACID Usage And Synthesis
| Chemical Properties | white to off-white crystalline powder |
| Uses | 5-Aminovaleric Acid is used in the development of drugs that halts severe type of seizures. |
| Uses | 5-Aminovaleric acid (5-AVA) is used:
- In the preparation of (5-AVA)x(MA)1-xPbI3, a perovskite for fabricating printable mesoscopic perovskite solar cell.
- As a spacer in the synthesis of rhenium and technetium-99m labeled insulin.
- To synthesize dipeptides that self-assemble to form nanotubes in the solid state as well as in solution over a wide range of pH.
- As a starting material in the total synthesis of an alkaloid, lycoposerramine Z.
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| Definition | ChEBI: A delta-amino acid comprising pentanoic acid with an amino substituent at C-5; a methylene homologue of gamma-aminobutyric acid (GABA) that is a weak GABA agonist. |
| reaction suitability | reaction type: solution phase peptide synthesis |
| Purification Methods | Crystallise it from H2O/EtOH. When heated above its melting point, it is converted to 2-piperidone with m 200o. [Wood & Colver J Am Chem Soc 67 654 1945, Beilstein 4 IV 2636.] |
5-AMINOVALERIC ACID Preparation Products And Raw materials
| Preparation Products | N-Succinimidyl 6-maleimidohexanoate-->delta-guanidinovaleric acid-->FMOC-5-AMINOPENTANOIC ACID-->N-Boc-cadaverine-->Boc-5-aminopentanoic acid-->MFCD01995662-->2-Piperidinone, 1-(3,5-dimethylphenyl)--->5-(1H-pyrrol-1-yl)pentanoic acid-->ETHYL 5-AMINOVALERATE |
