Introduction：Basic information about 5'-O-Dimethoxytrityl-deoxythymidine CAS 40615-39-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
5'-O-Dimethoxytrityl-deoxythymidine Basic information
| Product Name: | 5'-O-Dimethoxytrityl-deoxythymidine |
| Synonyms: | 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYTHYMIDINE;5'-O-[Bis(4-methoxyphenyl)benzyl]-2'-deoxythymidine;5-O-(4,4-DIMETHOXYTRITYL)THYMIDINE;5'-O-(DIMETHOXYTRITYL)-THYMIDINE;5'-O-(p,p'-dimethoxytrityl)thymidine;Dimethoxytrityl 5`-o-thymidine;5'-O-Dimethylterephthalate thymidine;5'-O-(4,4'-DIMETHOXYTRITYL)THYMIDINE, 98 % |
| CAS: | 40615-39-2 |
| MF: | C31H32N2O7 |
| MW: | 544.59 |
| EINECS: | 255-003-1 |
| Product Categories: | Biochemistry;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Bases & Related Reagents;Carbohydrates & Derivatives;Nucleotides;PNS |
| Mol File: | 40615-39-2.mol |
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5'-O-Dimethoxytrityl-deoxythymidine Chemical Properties
| Melting point | 114-116 °C (subl.)(lit.) |
| Boiling point | 618.41°C (rough estimate) |
| density | 1.2483 (rough estimate) |
| vapor pressure | 0Pa at 20℃ |
| refractive index | 7 ° (C=1, MeOH) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 9.55±0.10(Predicted) |
| form | Powder |
| color | White to off-white |
| Water Solubility | 3mg/L at 20℃ |
| BRN | 599297 |
| Stability: | Store in Freezer |
| InChIKey | UBTJZUKVKGZHAD-UPRLRBBYSA-N |
| SMILES | COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2O)N3C=C(C)C(=O)NC3=O)(c4ccccc4)c5ccc(OC)cc5 |
| LogP | 4.61 at 20℃ |
| CAS DataBase Reference | 40615-39-2(CAS DataBase Reference) |
| EPA Substance Registry System | Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]- (40615-39-2) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| F | 1-3-10 |
| Hazard Note | Irritant |
| TSCA | TSCA listed |
| HS Code | 29349990 |
| Storage Class | 13 - Non Combustible Solids |
| Hazard Classifications | Aquatic Chronic 4 |
5'-O-Dimethoxytrityl-deoxythymidine Usage And Synthesis
| Chemical Properties | White Powder |
| Uses | 5'-O-(4,4'-Dimethoxytrityl)thymidine is used in the solid-phase synthesis of polynucleotides and polythymidylic acids by the block coupling phosphotriester method. Further, it is used in the stereoselective synthesis of 3'-deoxy-3'-threo-hydroxymethyl nucleoside. In addition to this, it is used as a research tool for antiviral and anticancer studies. |
| General Description | 5′-O-(4,4′-Dimethoxytrityl)thymidine is a pyrimidine. |
| Flammability and Explosibility | Not classified |
5'-O-Dimethoxytrityl-deoxythymidine Preparation Products And Raw materials
| Preparation Products | 5'-O-(4,4'-DIMETHOXYTRITYL)-N4-BENZOYL-5-METHYL-2'-DEOXYCYTIDINE-->Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[P-methyl-N,N-bis(1-methylethyl)phosphonamidite], (S)- (9CI)-->DMT-dT Phosphoramidite |
