Introduction：Basic information about 7-Amino-3-cephem-4-carboxylic acid CAS 36923-17-8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
7-Amino-3-cephem-4-carboxylic acid Basic information
| Product Name: | 7-Amino-3-cephem-4-carboxylic acid |
| Synonyms: | Ceftizoxime Impurity 9;Ceftizoxime Impurity 16;7-NACA;7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;7-amino-8-oxo,(6R,7R)-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid;7-AMINO-3-NOR CEPHALOSPORANIC ACID(7-ANCA);5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-amino-8-oxo,(6R,7R)-;7-AMOCA |
| CAS: | 36923-17-8 |
| MF: | C7H8N2O3S |
| MW: | 200.21 |
| EINECS: | 609-312-7 |
| Product Categories: | Organic acids;Amines;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds |
| Mol File: | 36923-17-8.mol |
|
7-Amino-3-cephem-4-carboxylic acid Chemical Properties
| Melting point | 215-218°C |
| Boiling point | 536.9±50.0 °C(Predicted) |
| density | 1.69±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | Aqueous Acid (Slightly, Heated), DMSO (Slightly) |
| pka | 2.92±0.50(Predicted) |
| form | Solid |
| color | White to Off-White |
| Optical Rotation | 333.9° (C=0.01 g/ml, 1N NaHCO3, 20°C, 589nm) |
| InChI | InChI=1S/C7H8N2O3S/c8-4-5(10)9-3(7(11)12)1-2-13-6(4)9/h1,4,6H,2,8H2,(H,11,12)/t4-,6-/m1/s1 |
| InChIKey | RJFPBECTFIUTHB-INEUFUBQSA-N |
| SMILES | N12[C@@]([H])([C@H](N)C1=O)SCC=C2C(O)=O |
| CAS DataBase Reference | 36923-17-8(CAS DataBase Reference) |
Safety Information
7-Amino-3-cephem-4-carboxylic acid Usage And Synthesis
| Chemical Properties | Off-White Solid |
| Uses | 7-Amino-3-cephem-4-carboxylic acid is a reagent used in the preparation of Cephalosporin antibiotics. |
7-Amino-3-cephem-4-carboxylic acid Preparation Products And Raw materials
| Raw materials | 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-(hydroxymethyl)-8-oxo-7-[(2-phenylacetyl)amino]-, diphenylmethyl ester, (6R,7R)--->5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-formyl-8-oxo-7-[(2-phenylacetyl)amino]-, diphenylmethyl ester, (6R,7R)--->5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 8-oxo-7-[(2-phenylacetyl)amino]-, diphenylmethyl ester, (6R,7R)--->P-NITROBENZYL 7-PHENYLACETAMINO-3-HYDROXY-3-CEPHEM-4-CARBOXYLATE-->7-Amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenylmethyl ester-->7-Amino-3-chloro cephalosporanic acid |
