Introduction：Basic information about 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid CAS 86393-33-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Basic information
| Product Name: | 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid |
| Synonyms: | TIMTEC-BB SBB003016;1-CYCLOPROPYL-7-CHLORO-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLONE-3-CARBOXYLIC ACID;1-CYCLOPROPYL-6-FLUORO-7-CHLORO-1,4-DIHYDRO-4-OXO-3-QUINOLINIC CARBOXYLIC ACID;7-CHLORO-1-CYCLOPROPYL-1,4-DIHYDRO-6-FLUOROQUINOL-4-ONE-3-CARBOXYLIC ACID;7-CHLORO-1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-3-QUINOLINECARBOXYLIC ACID;7-CHLORO-1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID;7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID;7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXOHYDROQUINOLINE-3-CARBOXYLIC ACID |
| CAS: | 86393-33-1 |
| MF: | C13H9ClFNO3 |
| MW: | 281.67 |
| EINECS: | 405-050-0 |
| Product Categories: | alkyl chloride | alkyl Fluorine| carboxylic acid;Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Intermediates & Fine Chemicals;Pharmaceuticals;Heterocycles;Metabolites & Impurities;Ciprofloxacin;86393-33-1 |
| Mol File: | 86393-33-1.mol |
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7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Chemical Properties
| Melting point | 242-245 °C(lit.) |
| Boiling point | 467.3±45.0 °C(Predicted) |
| density | 1.652±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| pka | 6.36±0.41(Predicted) |
| form | Solid |
| color | Off-White to Light Yellow |
| InChI | InChI=1S/C13H9ClFNO3/c14-9-4-11-7(3-10(9)15)12(17)8(13(18)19)5-16(11)6-1-2-6/h3-6H,1-2H2,(H,18,19) |
| InChIKey | ISPVACVJFUIDPD-UHFFFAOYSA-N |
| SMILES | N1(C2CC2)C2=C(C=C(F)C(Cl)=C2)C(=O)C(C(O)=O)=C1 |
| CAS DataBase Reference | 86393-33-1(CAS DataBase Reference) |
Safety Information
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-36/37/38-52/53 |
| Safety Statements | 26-36-61-22 |
| WGK Germany | 2 |
| RTECS | VB1993795 |
| HazardClass | IRRITANT |
| HS Code | 29334900 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral
Aquatic Chronic 3 |
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Usage And Synthesis
| Chemical Properties | Off-White Crystalline Powder |
| Uses | An intermediate in the synthesis of Ciprofloxacin, a fluorinated quinolone antibacterial |
| Uses | 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic Acid (Ciprofloxacin EP Impurity A) is a metabolite of Ciprofloxacin, a fluorinated quinolone antibacterial. |
| General Description | 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, also known as fluoroquinolonic acid, can be prepared from ethyl 2,4-dichloro-5-fluorobenzoylacetate. It is formed as an intermediate during the synthesis of ciprofloxacin hydrochloride, a fluorinated quinolone antibacterial drug. |
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Preparation Products And Raw materials
| Preparation Products | λ-Cyhalothrin-->Ciprofloxacin Related CoMpound-->DESETHYLENE CIPROFLOXACIN, HYDROCHLORIDE-->7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER-->Enrofloxacin |
