Introduction：Basic information about ABD-F CAS 91366-65-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
ABD-F Basic information
| Product Name: | ABD-F |
| Synonyms: | 4-Fluoro-7-sulfobenzofurazan;[=4-(AMinosulfonyl)-7-fluoro-2,1,3-benzoxadiazole] [HPLC Labeling Reagent for DeterMination of Thiols];ABD-F 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazol;4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazol, 98%, derivatization grade;7-Fluorobenzoc1,2,5oxadiazole-4-sulfonamide;4-(AMinosulfonyl)-7-fluoro-2,1,3-benzoxadiazol, derivatization grade;ABD-F |
| CAS: | 91366-65-3 |
| MF: | C6H4FN3O3S |
| MW: | 217.18 |
| EINECS: | |
| Product Categories: | Chemical and pharmaceutical intermediates;pharmaceutical intermediates;Analytical Chemistry;Fluorescence Detection (HPLC Labeling Reagents);HPLC Labeling Reagents;Mercapto Group Labeling Reagents for Fluorescence HPLC;Fluorescent Labels & Indicators;MTS & Sulfhydryl Active Reagents;Fluorescent Labels and Indicators |
| Mol File: | 91366-65-3.mol |
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ABD-F Chemical Properties
| Melting point | 143-145°C |
| Boiling point | 408.8±55.0 °C(Predicted) |
| density | 1.724±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO: soluble |
| form | White to yellow crystalline powder. |
| pka | 9.08±0.30(Predicted) |
| color | Off-White to Pale Yellow |
| BRN | 5035147 |
| Stability: | Light Sensitive |
| InChI | InChI=1S/C6H4FN3O3S/c7-3-1-2-4(14(8,11)12)6-5(3)9-13-10-6/h1-2H,(H2,8,11,12) |
| InChIKey | XROXHZMRDABMHS-UHFFFAOYSA-N |
| SMILES | N1=C2C(F)=CC=C(S(N)(=O)=O)C2=NO1 |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 26-36/37/39-24/25 |
| WGK Germany | 3 |
| F | 3-10 |
| Hazard Note | Irritant |
| HS Code | 29350090 |
ABD-F Usage And Synthesis
| Chemical Properties | Light Yellow Solid |
| Uses | Highly reactive fluorogenic reagent for the labeling of thiols for HPLC. ABD-F is nonfluorescent until reacted with thiols and therefore can be used to quantitate thiols in solution, as well as thiols separated by HPLC or TLC. |
| Uses | A water soluble pH dependent bifunctional fluorogenic reagent for the sensitive and specific detection of protein thiols. ABD-F is highly reactive and specific for protein thiols, and its selectivity is superior to that of other sulfhydryl-reactive fluorophores such as fluorescein maleimide, 5-iodoacetamidofluorescein, 5-I-AEDANS, dansylaziridine, and bimane. Fluorescence: max Abs. l = 385nm, max Em. l = 520nm; Molar Abs. > 4.5x103 (ca. 315nm) |
| Uses | Reagent for fluorimetric assay of thiols. |
| General Description | 4-Fluoro-7-sulfamoylbenzofurazan is a fluorescent reagent, which directly links to the sulfur atom of thiols without a flexible alkyl chain. It is used to detect low molecular thiols using high performance liquid chromatography. |
ABD-F Preparation Products And Raw materials
