Alcuronium Chloride CAS 15180-03-7

Introduction：Basic information about Alcuronium Chloride CAS 15180-03-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Alcuronium Chloride Basic information

• Product Name: Alcuronium Chloride
• Synonyms: Alcuronium;Alcuronium dichloride;N,N′-Diallylnortoxiferinium dichloride;Alcuronium chloride CRS;Alcuronium Chloride USP/EP/BP
• CAS: 15180-03-7
• MF: C44H50N4O2.2Cl
• MW: 737.811
• EINECS: 239-229-8
• Mol File: 15180-03-7.mol

Alcuronium Chloride Chemical Properties

• alpha: D22 -348° (methanol)

Safety Information

• RIDADR: 3249
• HazardClass: 6.1(a)
• PackingGroup: II

Alcuronium Chloride Usage And Synthesis

Originator

Alloferin, Roche ,UK ,1966

Uses

Alcuronium Dichloride exists as a neuromuscular blocking agent with ganglion blocking activity. Binds to muscarinic M2 receptors.

Definition

ChEBI: Alcuronium chloride is chloride salt of alcuronium. It contains an alcuronium.

Manufacturing Process

31 g of diallylnortoxiferine diiodide are suspended in 1 liter of water andshaken with 1,100 ml of Amberlite IRA-400 [chloride ion form, describedMerck Index, 7th edition, Merck and Co., Inc., Rahway, New Jersey (1960),page 1584], for 2 hours. The diiodide thereby goes into solution. The ionexchanger is filtered off and then washed in 3 portions with a total of 1 liter ofwater. The combined filtrates are then allowed to run through a column of 300ml of Amberlite IRA-400 (chloride ion form), rinsed with 300 ml of water andthe eluate evaporated to dryness in a vacuum while excluding air. The residuegives on recrystallization from methanol/ethanol crystalline pure colorlessdiallylnortoxiferine dichloride in a yield of 18.6 g. The compound contains 5mols of water of crystallization after equilibration in air.

Brand name

Alloferin (Hoffmann-LaRoche-International).

Therapeutic Function

Muscle relaxant