Introduction：Basic information about ALDOLASE CAS 9024-52-6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
ALDOLASE Basic information
| Product Name: | ALDOLASE |
| Synonyms: | ALDOLASE AMMONIUM SULFATE;ALDOLASE;ALDOLASE RABBIT MUSCLE;aldolasefromtroutmuscle;D-FRUCTOSE-1,6-BISPHOPHATE-D-GLYCERALDEHYDE-3-PHOSPHATE-LYASE;D-FRUCTOSE-1,6-BISPHOSPHATE-D-GLYCERALDEHYDE-3-PHOSPHATE-LYASE;EC 4.1.2.13;IUB: 4.1.2.13 |
| CAS: | 9024-52-6 |
| MF: | n.a. |
| MW: | 0 |
| EINECS: | 232-781-0 |
| Product Categories: | Mass Spectrometry;P;PON - PT;Proteomics;Peptide and protein standards for mass spectrometry analysisAlphabetic |
| Mol File: | Mol File |
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ALDOLASE Chemical Properties
| storage temp. | -20°C |
| form | powder |
| color | white |
| biological source | rabbit muscle |
| Specific Activity | 10-20units/mg protein |
| EPA Substance Registry System | Aldolase, fructose diphosphate (9024-52-6) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-24/25-22 |
| WGK Germany | 3 |
| F | 10-21 |
| TSCA | TSCA listed |
| Storage Class | 12 - Non Combustible Liquids |
ALDOLASE Usage And Synthesis
| Chemical Properties | White needle-like crystals or lyophilized powder, soluble in water, pI 6.1, optimum pH 7.0. Stability: dry powder can be stored for one year at 4 ℃; the commercial product is a suspension of 3.2 mol/L ammonium sulphate solution, which can be stable for six months at 4 ℃. Inhibitors are metal ions (Cu2+, Ag+, Zn2+), iodine, o-phenanthroline, adenosine nucleoside phosphate (ATP> ADP> AMP), pyridoxal phosphate, D-arachidonitol-1,5-bisphosphate (KI=1.5 μmol/L), urea (4 mol/L) N-bromide acetoacethanol ammonium. Enzyme reaction: D-fructose-1,6-bisphosphate ═dihydroxyacetone phosphate + D-glyceraldehyde-3-phosphate. |
| Uses | Aldolase from rabbit muscle has been used:
- in standard 1-phosphofructokinase from rabbit muscle (RPFK-1) assay
- as a standard in the characterization of metabolic enzymes from glaucomatous tissues
- in fructose 2,6-bisphosphate assay of human cell lines
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| Uses | Aldolase is used to convert fructose 1,6-diphosphate to dihydroxyacetone phosphate and glyceraldehyde 3-phosphate. Aldolase, from rabbit muscle has been used for stereospecific deprotonation at DHAP C3 . Product A2714 is essentially sulfate-free and contains citrate buffer salts. |
| Definition | An enzyme present in muscle involved in glycogenolysis and anaerobic glycolysis. It catalyzes production of dihydroxyacetone phosphate and phosphoglyceric aldehyde from fructose-1,6-diphosphate. |
| General Description | Aldolase exists as three isoforms in rabbit, which includes type A from muscle, type B from liver and brain associated type C. Aldolases correspond to a molecular weight of 158 kDa and exists as tetramer. |
| Biochem/physiol Actions | Aldolase interaction with Wiskott-Aldrich syndrome protein (WASP) may modulate actin dynamics. It reverses the inhibition elicited by ascorbate on Muscle-type LDH (LDH-m4). |
ALDOLASE Preparation Products And Raw materials
| Raw materials | Ammonium sulfate |
