Introduction：Basic information about asebogenin CAS 520-42-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
asebogenin Basic information
| Product Name: | asebogenin |
| Synonyms: | asebogenin;1-(2,6-Dihydroxy-4-methoxyphenyl)-3-(4-hydroxyphenyl)-1-propanone;4'-O-Methylphloretin;1-Propanone, 1-(2,6-dihydroxy-4-methoxyphenyl)-3-(4-hydroxyphenyl)-;Asebogenin, 10 mM in DMSO;Dihydroisosakuranetin |
| CAS: | 520-42-3 |
| MF: | C16H16O5 |
| MW: | 288.3 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 520-42-3.mol |
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asebogenin Chemical Properties
| Melting point | 168℃ |
| Boiling point | 550.9±50.0 °C(Predicted) |
| density | 1.325±0.06 g/cm3(Predicted) |
| pka | 7.00±0.40(Predicted) |
Safety Information
asebogenin Usage And Synthesis
| Uses | Asebogenin has antimalarial activity in vitro[1]. Asebogenin can inhibit the phosphorylation of Syk, thereby effectively suppressing platelet activation and the formation of neutrophil extracellular traps[2]. |
| Definition | ChEBI: A member of the class of dihydrochalcones that is the 4'-methyl ether derivative of phloretin. |
| References | [1] 1.Jenett-Siems K, et al. n vitro antiplasmodial activity of Central American medicinal plants. Trop Med Int Health. 1999 Sep;4(9):611-5. DOI:10.1046/j.1365-3156.1999.00456.x
[2] Li L, et al. Asebogenin suppresses thrombus formation via inhibition of Syk phosphorylation. Br J Pharmacol. 2023 Feb;180(3):287-307. DOI:10.1111/bph.15964 |
asebogenin Preparation Products And Raw materials
