Introduction：Basic information about Azatadine CAS 3964-81-6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Azatadine Basic information
| Product Name: | Azatadine |
| Synonyms: | 6,11-Dihydro-11-(1-methyl-4-piperidylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine;6,11-Dihydro-11-(1-methylpiperidin-4-ylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine;6,11-Dihydro-11-(1-Methyl-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine;5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 6,11-dihydro-11-(1-Methyl-4-piperidinylidene)-;Desloratadine Impurity 25;AZATADINE;11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine;Azatadine USP/EP/BP |
| CAS: | 3964-81-6 |
| MF: | C20H22N2 |
| MW: | 290.4 |
| EINECS: | |
| Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals |
| Mol File: | 3964-81-6.mol |
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Azatadine Chemical Properties
| Melting point | 124-126° |
| Boiling point | 450.1±45.0 °C(Predicted) |
| density | 1.127 |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | Powder |
| pka | 8.74±0.20(Predicted) |
Safety Information
Azatadine Usage And Synthesis
| Uses | Antihistaminic. |
| Definition | ChEBI: A benzo[5,6]cyclohepta[1,2-b]pyridine having a 1-methylpiperidin-4-ylidene group at the 11-position. |
| Brand name | Optimine (Schering). |
Azatadine Preparation Products And Raw materials
| Raw materials | 2-Pyridinecarbonitrile, 3-(2-phenylethyl)--->5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one-->6-11-dihydro-11-(1-methylpiperidin-4-yl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol-->N-T-BUTYL-3-METHYL PYRIDINE-2-CARBOXAMIDE-->1-Methylpiperdin-4-ylmagnesium chloride, 0.50 M in THF-->Benzyl chloride-->N-Methyl Desloratadine |
