Benzyltriphenylphosphonium chloride CAS 1100-88-5
Introduction：Basic information about Benzyltriphenylphosphonium chloride CAS 1100-88-5, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Benzyltriphenylphosphonium chloride Basic information
| Product Name: | Benzyltriphenylphosphonium chloride |
| Synonyms: | (phenylmethyl)triphenyl-phosphoniuchloride;(phenylmethyl)triphenylphosphoniumchloride;Benzyltriphenylchlorophosphine;benzyltriphenylphosphonidechloride;benzyltriphenyl-phosphoniuchloride;Phosphonium,triphenyl(phenylmethyl)-,chloride;triphenyl(phenylmethyl)-phosphoniuchloride;triphenyl(phenylmethyl)phosphoniumchloride |
| CAS: | 1100-88-5 |
| MF: | C25H22ClP |
| MW: | 388.87 |
| EINECS: | 214-154-3 |
| Product Categories: | organophosphorus compound;C-C Bond Formation;Olefination;Wittig Reagents;Pharmaceutical Intermediates;Miscellaneous Compounds;Phosphonium Compounds;Synthetic Organic Chemistry;Wittig & Horner-Emmons Reaction;Wittig Reaction |
| Mol File: | 1100-88-5.mol |
Benzyltriphenylphosphonium chloride Chemical Properties
| Melting point | ≥300 °C (lit.) |
| density | 1.18 g/cm3 (20℃) |
| vapor pressure | 0.1 hPa |
| Fp | 300°C |
| storage temp. | Store at <= 20°C. |
| form | Crystalline Powder |
| color | White to almost white |
| Water Solubility | SOLUBLE |
| Sensitive | Hygroscopic |
| BRN | 3599868 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| InChI | 1S/C25H22P.ClH/c1-5-13-22(14-6-1)21-26(23-15-7-2-8-16-23,24-17-9-3-10-18-24)25-19-11-4-12-20-25;/h1-20H,21H2;1H/q+1;/p-1 |
| InChIKey | USFRYJRPHFMVBZ-UHFFFAOYSA-M |
| SMILES | [Cl-].C(c1ccccc1)[P+](c2ccccc2)(c3ccccc3)c4ccccc4 |
| LogP | -0.7 at 20℃ |
| CAS DataBase Reference | 1100-88-5(CAS DataBase Reference) |
| EPA Substance Registry System | Phosphonium, triphenyl(phenylmethyl)-, chloride (1100-88-5) |
Safety Information
| Hazard Codes | T,Xi |
| Risk Statements | 25-36/37/38-24/25 |
| Safety Statements | 26-36/37/39-45-36 |
| RIDADR | UN 2811 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | TA2416500 |
| TSCA | TSCA listed |
| HazardClass | 6.1 |
| PackingGroup | II |
| HS Code | 29310095 |
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
| Hazard Classifications | Acute Tox. 2 Inhalation Acute Tox. 2 Oral Aquatic Acute 1 Aquatic Chronic 1 Eye Dam. 1 STOT RE 1 STOT SE 3 |
| Toxicity | LD50 orally in Rabbit: 43 mg/kg |
| Chemical Properties | Benzyltriphenylphosphonium Chloride is a white to off white powder, It is highly soluble in water and polarizable solvents. It is a quaternary phosphonium salt mainly used in organic synthesis as a wittig reagent and as a phase transfer catalyst in the production of fluoroelastomers and printing inks. |
| Uses | Benzyltriphenylphosphonium Chloride was used as a reagent in the organic synthesis of several compounds including that of stabilised phosphonium ylides containing saturated oxygen heterocycles. Also used in the synthesis of novel substituted cis-stilbene derivatives which display antimicrobial activity. |
| Application | Benzyltriphenylphosphonium chloride can be used as a reactant for the synthesis of: Platinum chloro-tetrazole complexes via azidation. Trans-stilbenes and cinnamates via Wittig olefination. Achiral N-hydroxyformamide inhibitors of ADAM-TS4 and ADAM-TS5 for osteoarthritis treatment. Pentiptycenes for use as light-driven molecular brakes. Archipelago structures for formation of petroleum asphaltenes. It is also used as a crosslinking agent for tube-like natural halloysite / fluorelastomer nanocomposites. Crosslinking agent for tube-like natural halloysite / fluorelastomer nanocomposites Reactant for synthesis of: Platinum chloro tetrazole complexes via azidation Trans-stilbenes and cinnamates via Wittig olefination Achiral N-hydroxyformamide inhibitors of ADAM-TS4 and ADAM-TS5 for osteoarthritis treatment Pentiptycenes for use as light-driven molecular brakes Reactant for formation of archipelago structures for formation of petroleum asphaltenes |
| Flammability and Explosibility | Not classified |
| reaction suitability | reaction type: C-C Bond Formation |
| Purification Methods | Wash it with Et2O and crystallise it from EtOH (six-sided plates). It is hygroscopic and forms crystals with one molecule of H2O. [Michaelis & Soden Justus Liebigs Ann Chem 229 320 1885, Kr.hnke Chem Ber 83 291 1950, Beilstein 16 IV 994.] |
Benzyltriphenylphosphonium chloride Preparation Products And Raw materials
| Raw materials | 3-Cyanopyridine |
| Preparation Products | Sulindac-->Flunarizine EP Impurity D-->(Z)-Cinnarizine |
