Introduction：Basic information about Bromoacetaldehyde CAS 17157-48-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Bromoacetaldehyde Basic information
| Product Name: | Bromoacetaldehyde |
| Synonyms: | 2-BROMOACETALDEHYDE;Acetaldehyde, bromo-(6CI,7CI,8CI,9CI);bromoacetaldehyde ISO 9001：2015 REACH;BromoacetaldehydeDISCONTINUED, offer stable form B678880;Bromoacetaldehyde |
| CAS: | 17157-48-1 |
| MF: | C2H3BrO |
| MW: | 122.95 |
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| Product Categories: | |
| Mol File: | 17157-48-1.mol |
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Bromoacetaldehyde Chemical Properties
| Melting point | 136-138 °C |
| Boiling point | 109.35°C (estimate) |
| density | 1.7515 (rough estimate) |
| refractive index | 1.4486 (estimate) |
| EPA Substance Registry System | Acetaldehyde, bromo- (17157-48-1) |
Safety Information
| RIDADR | UN2927 |
| HazardClass | 6.1, 8 |
Bromoacetaldehyde Usage And Synthesis
| Uses | Bromoacetaldehyde can be used as an intermediate in pharmaceutical and chemical synthesis, mainly in laboratory research and development and chemical production processes. |
| Definition | ChEBI:2-Bromoacetaldehyde is an organobromine compound. |
| Synthesis | Preparation of Bromoacetaldehyde:1,4-dibromo-trans-2-butene(10g, 0.046 mol) was dissolved in dry CH2CI2 (100 ml) and cooled to -780℃ and ozone gas was bubbled until the blue color persisted (~30 min). A nitrogen stream was passed through the solution until the blue color disappeared, giving colorless solution. Triphenyl phosphine (12.9g, 0.046 mol) was added portion wise over a period EPO of 1 hr. The reaction mixture was brought to 0℃ and kept in the refrigerator for 15 hrs. The solvent (CH2CI2) was removed from the reaction mixture (without applying vacuum) and the thick residue was distilled at 400℃ under vacuum (1mm Hg), maintaining the temperature of the receiving flask at -780℃. (during distillation, special care was taken to maintain a cold water circulation (~0°C to - 50℃)). The bromoacetaldehyde(2.8g, yield = 50%) was obtained as a light yellow liquid.
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Bromoacetaldehyde Preparation Products And Raw materials
| Preparation Products | 6,8-DIBROMOIMIDAZO[1,2-A]PYRAZINE-->3-Butenoic acid, 4-hydroxy-, gamma-lactone-->Imidazo[1,2-a]pyridine, 6-fluoro- (9CI)-->METHYL IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLATE-->8-Chloro-imidazo[1,2-a]pyrazine-->Oxazole-2-amine-->IMidazo[1,2-a]pyridine, 8-chloro-6-(trifluoroMethyl)--->Bromoacetaldehyde dimethyl acetal |
