B-SITOSTENONE CAS 1058-61-3
Introduction：Basic information about B-SITOSTENONE CAS 1058-61-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
B-SITOSTENONE Basic information
| Product Name: | B-SITOSTENONE |
| Synonyms: | STIGMAST-4-EN-3-ONE;SITOSTENONE, BETA-;(24R)-24-Ethylcholest-4-en-3-one;3-Keto-β-cytostenol;3-Oxo-Δ4,5-sitosterone;Stigmastenone;β-Sitostenone;4-Stigmasten-3-one |
| CAS: | 1058-61-3 |
| MF: | C29H48O |
| MW: | 412.69 |
| EINECS: | |
| Product Categories: | Steroids |
| Mol File: | 1058-61-3.mol |
B-SITOSTENONE Chemical Properties
| Melting point | 82 °C(Solv: methanol (67-56-1)) |
| Boiling point | 503.8±17.0 °C(Predicted) |
| density | 0.97±0.1 g/cm3(Predicted) |
| solubility | DMF: 0.33 mg/ml Ethanol: Slightly soluble |
| form | Solid |
| color | White to off-white |
| LogP | 10.240 (est) |
| EPA Substance Registry System | Stigmast-4-en-3-one (1058-61-3) |
Safety Information
| Uses | β-Sitostenone is a sterols that can be isolated from Cochlospermum vitifolium.β-Sitostenone inhibits tyrosinase activity, and has anti-melanogenic and anti-tumor activities[1][2][3]. |
| Definition | ChEBI: Beta-sitostenone is a steroid and a C29-steroid. It has a role as a metabolite. It derives from a hydride of a stigmastane. |
| IC 50 | Human Endogenous Metabolite |
| References | [1] Aguilar-Guadarrama AB, et al. Flavonoids, Sterols and Lignans from Cochlospermum vitifolium and Their Relationship with Its Liver Activity. Molecules. 2018 Aug 5;23(8):1952. DOI:10.3390/molecules23081952 [2] Chu CW, et al. Biofunctional Constituents from Michelia compressa var. lanyuensis with Anti-Melanogenic Properties. Molecules. 2015 Jul 3;20(7):12166-74. DOI:10.3390/molecules200712166 [3] Fan SQ, et al. Sarocladione, a unique 5,10:8,9-diseco-steroid from the deep-sea-derived fungus Sarocladium kiliense. Org Biomol Chem. 2019 Jun 18;17(24):5925-5928. DOI:10.1039/c9ob01159e [4] SUPINYA TEWTRAKUL Sanan S. Effects of compounds from Kaempferia parviflora on nitric oxide, prostaglandin E2 and tumor necrosis factor-alpha productions in RAW264.7 macrophage cells[J]. Journal of ethnopharmacology, 2008, 120 1: Pages 81-84. DOI: 10.1016/j.jep.2008.07.033 [5] KHINE SWE NYUNT. Isolation of antitrypanosomal compounds from Vitis repens, a medicinal plant of Myanmar.[J]. Natural Product Communications, 2012, 7 5: 609-610. [6] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras. [7] RUBY LISA ALEXANDER-LINDO Muraleedharan G N E Y St A Morrison. Hypoglycaemic effect of stigmast-4-en-3-one and its corresponding alcohol from the bark of Anacardium occidentale (cashew).[J]. Phytotherapy Research, 2004, 18 5: 403-407. DOI: 10.1002/ptr.1459 |
B-SITOSTENONE Preparation Products And Raw materials
| Preparation Products | stigmast-4-ene-3,6-dione |
