CARBOXYPEPTIDASE B CAS 80651-95-2

Introduction：Basic information about CARBOXYPEPTIDASE B CAS 80651-95-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

CARBOXYPEPTIDASE B Basic information

• Product Name: CARBOXYPEPTIDASE B
• Synonyms: CARBOXYPEPTIDASE B, PORCINE PANCREAS;IUB: 3.4.17.2;EC 3.4.17.2;SUC-ALA-ALA-PRO-PHE-SBZL;SUC-ALA-ALA-PRO-PHE THIOBENZYL ESTER;PEPTIDYL-L-LYSINE[L-ARGININE] HYDROLASE;PROTAMINASE;PROTEIN CARBOXYPEPTIDASE B
• CAS: 80651-95-2
• MF: C31H38N4O7S
• MW: 610.73
• EINECS: 232-788-9
• Mol File: 80651-95-2.mol

CARBOXYPEPTIDASE B Chemical Properties

• Boiling point: 966.7±65.0 °C(Predicted)
• density: 1.291±0.06 g/cm3(Predicted)
• storage temp.: avoid repeated freeze/thaw cycles
• form: powder
• pka: 4.69±0.10(Predicted)
• color: white
• Sequence: Suc-Ala-Ala-Pro-Phe-SBzl

Safety Information

• Hazard Codes: Xi,B
• Risk Statements: 36
• Safety Statements: 26-36
• WGK Germany: 3

CARBOXYPEPTIDASE B Usage And Synthesis

Description

Carboxypeptidase B is an enzyme that specifically releases C-terminal lysine and arginine from substrates, and it was initially named "basic carboxypeptidase". It is distinguished from Anson's carboxypeptidase A and is also known as protaminase.

Characteristics

Carboxypeptidase B catalyzes hydrolysis of the basic amino acids lysine, arginine and ornithine from the C-terminal end of polypeptides. The molecular weight is 34,500 daltons, the pH optimum is 7.9, and the pI is 6.0.

Uses

Carboxypeptidase B has been used for the mass spectroscopy analysis ofanti-K11/K48 bispecific antibody.

General Description

Peptidyl-L-lysine (-L-arginine) hydrolase. Carboxypeptidase B is secreted as a zymogen (pro-carboxypeptidase B) from the pancreas.

Biochem/physiol Actions

Carboxypeptidase B is a Zn2+-metalloprotease, which catalyzes the hydrolysis of the basic amino acids L-Lys and L-Arg from the C-terminal position in polypeptides.