caudatin CAS 38395-02-7

Introduction：Basic information about caudatin CAS 38395-02-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

caudatin Basic information

• Product Name: caudatin
• Synonyms: caudatin;(3beta,12beta,14beta,17alpha)-12-[[(2E)-3,4-Dimethyl-1-oxo-2-pentenyl]oxy]-3,8,14,17-tetrahydroxypregn-5-en-20-one;Caudatin ,98%;Pregn-5-en-20-one,12-[[(2E)-3,4-dimethyl-1-oxo-2-pentenyl]oxy]-3,8,14,17-tetrahydroxy-, (3b,12b,14b,17a)-;Pregn-5-en-20-one, 12-[[(2E)-3,4-dimethyl-1-oxo-2-pentenyl]oxy]-3,8,14,17-tetrahydroxy-, (3β,12β,14β,17α)-;[(3S,8S,9R,10R,12R,13S,14R,17R)-17-acetyl-3,8,14,17-tetrahydroxy-10,13-dimethyl-1,2,3,4,7,9,11,12,15,16-decahydrocyclopenta[a]phenanthren-12-yl] (E)-3,4-dimethylpent-2-enoate;Caudatin-RM;Caudatin, 10 mM in DMSO
• CAS: 38395-02-7
• MF: C28H42O7
• MW: 490.63
• Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 38395-02-7.mol

caudatin Chemical Properties

• Boiling point: 617.9±55.0 °C(Predicted)
• density: 1.25
• storage temp.: 4°C, protect from light
• solubility: DMF:30.0(Max Conc. mg/mL);61.15(Max Conc. mM) DMSO:30.0(Max Conc. mg/mL);61.15(Max Conc. mM) Ethanol:30.0(Max Conc. mg/mL);61.15(Max Conc. mM) Ethanol:PBS (pH 7.2) (1:7):0.12(Max Conc. mg/mL);0.24(Max Conc. mM)
• form: A solid
• pka: 11.93±0.70(Predicted)
• color: White to off-white
• Major Application: food and beverages
• InChIKey: VWLXIXALPNYWFH-NLCMXFOFNA-N
• SMILES: [C@]12(C)[C@H](OC(=O)/C=C(\C)/C(C)C)C[C@]3([H])[C@@]4(C)CC[C@H](O)CC4=CC[C@@]3(O)[C@@]1(O)CC[C@]2(O)C(C)=O |&1:0,2,13,15,19,25,27,31,r|

Safety Information

• WGK Germany: WGK 3
• Storage Class: 11 - Combustible Solids

caudatin Usage And Synthesis

Chemical Properties

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents.

Uses

Gaodatin has inhibitory effect on the growth of various human-derived tumor cell lines such as human gastric cancer, colon cancer, and lung cancer.

Biological Activity

Caudatin, a C-21 steroid hormone derived from Cynanchum auriculatum (C. auriculatum), potently inhibits human glioma growth in vitro and in vivo by triggering cell cycle arrest and apoptosis.