Introduction：Basic information about Cefodizime sodium CAS 86329-79-5, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Cefodizime sodium Basic information
| Product Name: | Cefodizime sodium |
| Synonyms: | )(methoxyimino)acetyl)amino)-3-(((5-(carboxymethyl)-4-methyl-2-thiazolyl)thio;7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((5-(carboxymethyl)-4-methyl-2-thiazolyl)th5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicaci;7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid;disodiumsalt,(6r-(6-alpha,7-beta(z)))-)methyl)-8-oxo;thr-221;7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((5-(carboxymethyl)-4-methyl-2-thiazolyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid disodium salt;Cefodizimedisodiumsalt;kenicef |
| CAS: | 86329-79-5 |
| MF: | C20H21N6NaO7S4 |
| MW: | 608.65 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 86329-79-5.mol |
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Cefodizime sodium Chemical Properties
| Melting point | 196 - 207°C |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Sparingly) |
| form | powder |
| color | White to Off-White |
| biological source | synthetic |
| Water Solubility | H2O: soluble 270mg/mL |
| Stability: | Hygroscopic |
| InChIKey | LTIUKZADMUEHDC-LJYFWBPINA-N |
| SMILES | C(C1=C(CS[C@]2([H])[C@H](NC(=O)/C(/C3=CSC(N)=N3)=N\OC)C(=O)N12)CSC1=NC(C)=C(CC(=O)O)S1)(=O)O.[NaH] |&1:5,7,r| |
| CAS DataBase Reference | 86329-79-5(CAS DataBase Reference) |
Safety Information
| WGK Germany | WGK 2 |
| Storage Class | 13 - Non Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 |
| Toxicity | LD50 in mice, rabbits (mg/kg): 4000-8000 i.v. both species; in rats (mg/kg): 4000-8000 i.v., 15000-17500 s.c., 8000-11000 i.p. (Bryskier) |
Cefodizime sodium Usage And Synthesis
| Description | Cefodizirne sodium is a parenteral, long-acting, broad-spectrum cephalosporin useful in the treatment of bacterial infections. It is efficacious against pathogens resistant topenicillins and older cephalosporins. An indication under study is its reportedimmunostimulatory activity. |
| Originator | Hoechst AG (Germany) |
| Uses | Cefodizime Sodium (cas# 86329-79-5) is a compound useful in organic synthesis. |
| Definition | ChEBI: Cefodizime sodium is a cephalosporin. |
| Brand name | Neucef; Kenicef |
| Hazard | Low toxicity by ingestion. |
| Biochem/physiol Actions | Cefodizime is a third generation cephalosporin with a broad spectrum of antibacterial activity. Cefodizime was demonstrated to be effective against upper and lower respiratory tract infections, urinary tract infections, and gonorrhea. Cefodizime regulates the cytokines expression of neutrophils through toll-like receptor 4 (TLR-4) stimulated by Klebsiella pneumonie. |
Cefodizime sodium Preparation Products And Raw materials
| Preparation Products | T 2588G-->desacetylcefotaxime-->2-Mercapto-4-methyl-5-thiazoleacetic acid |
