Introduction：Basic information about CORYNANTHINE CAS 483-10-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
CORYNANTHINE Basic information
| Product Name: | CORYNANTHINE |
| Synonyms: | CORYNANTHINE DIHYDRATE;corynanthine free base;methyl (16beta,17alpha)-17-hydroxyyohimban-16-carboxylate;CORYNANTHINE HCL(RG);RAUHIMBINE;Corynanthin;Coynanthine;Nsc407306 |
| CAS: | 483-10-3 |
| MF: | C21H26N2O3 |
| MW: | 354.44 |
| EINECS: | 207-590-0 |
| Product Categories: | Alkaloids |
| Mol File: | 483-10-3.mol |
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CORYNANTHINE Chemical Properties
| Melting point | 225-230°C |
| alpha | D19 -85° (c = 0.5 in pyridine) |
| storage temp. | 2-8°C |
| LogP | 2.200 (est) |
Safety Information
| Risk Statements | 25 |
| Safety Statements | 1-20-45 |
| RIDADR | 1544 |
| WGK Germany | 3 |
CORYNANTHINE Usage And Synthesis
| Description | This alkaloid has been isolated by Hoffmann from the bark of Rauwolfia serpentina. It forms colourless crystals from Me2CO and has [α]20D - 82° (c 0.5, pyridine). |
| Uses | Corynanthine is a selective α1-adrenergic receptor antagonist. Corynanthine can significantly lower intraocular pressure in rabbits[1]. |
| Definition | ChEBI: Corynanthine is a yohimban alkaloid. |
| References | Hoffmann., Helv. Chim. Acta, 37,314,849 (1954) |
CORYNANTHINE Preparation Products And Raw materials
