Introduction：Basic information about CRF (HUMAN, RAT) CAS 86784-80-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
CRF (HUMAN, RAT) Basic information
| Product Name: | CRF (HUMAN, RAT) |
| Synonyms: | CORTICOTROPIN RELEASING FACTOR;CORTICOTROPIN RELEASING FACTOR (CRF), HUMAN, RAT;CORTICOTROPIN RELEASING FACTOR, HUMAN;CORTICOTROPIN RELEASING FACTOR, HUMAN AND RAT;CORTICOTROPIN RELEASING FACTOR HUMAN, RAT;CRF, HUMAN AND RAT;CRF (HUMAN, RAT);CRH |
| CAS: | 86784-80-7 |
| MF: | C208H344N60O63S2 |
| MW: | 4757.45 |
| EINECS: | |
| Product Categories: | proteins;Peptide;CRF receptor and related |
| Mol File: | Mol File |
|
CRF (HUMAN, RAT) Chemical Properties
| storage temp. | −20°C |
| solubility | H2O : 16.66 mg/mL (3.50 mM; Need ultrasonic and warming) |
| form | White to off-white lyophilized solid |
| color | white to off-white |
| biological source | human
rat |
| Water Solubility | Soluble to 1.10 mg/ml in water |
| InChIKey | VXFVFWFSJFSXHN-FAUHKOHMSA-N |
Safety Information
| WGK Germany | 3 |
| RTECS | GM7925000 |
| F | 10 |
| HS Code | 2937190000 |
| Storage Class | 11 - Combustible Solids |
CRF (HUMAN, RAT) Usage And Synthesis
| Uses | Treatment of symptoms associated with peritumoral edema in brain tumor patients. |
| Uses | Corticotropin Releasing Factor human, rat has been used:
- as a component in Dulbecco′s modified eagle medium (DMEM) for incubating lung explants
- as a component in serum-free complete medium for isolation and culturing of fetal distal lung epithelial cells
- in the synthesis of the corticotropin-releasing factor(CRF)-TAMRA?1?mixture
- in chronic intracerebroventicular administration, to study its effect on hypoxia in hippocampus
|
| Brand name | Xerecept (Hollister-Stier) [Note—The source of the product (human, porcine, etc.) must be indicated in the labeling.]. |
| General Description | Corticotropin-releasing factor is a 41-amino-acid polypeptide. It is expressed in neurons, hypothalamus?and amygdala. |
| Biochem/physiol Actions | CRF is a hypothalamic peptide that releases ACTH and endorphin from the anterior pituitary. It is also a neurotransmitter in the central nervous system, and is involved in autonomic and endocrine responses to stress. |
| storage | Store at -20°C |
CRF (HUMAN, RAT) Preparation Products And Raw materials
