Introduction：Basic information about DEPBT CAS 165534-43-0, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
DEPBT Basic information
| Product Name: | DEPBT |
| Synonyms: | DEPBT;DIETHYL-(4-OXO-3H-1,2,3-BENZOTRIAZIN-3-YL)PHOSPHATE;DIETHYL 3,4-DIHYDRO-4-OXO-1,2,3-BENZOTRIAZIN-3-YL PHOSPHATE;3-DIETHOXYPHOSPHORYL-1,2,3-BENZOTRIAZIN-4(3H)-ONE;3-(DIETHOXYPHOSPHORYLOXY)-1,2,3-BENZOTRIAZIN-4(3H)-ONE;3-(Diethoxyphosphoryloxy)-1,2,3-benzotrizin-4(3H)-one;Diethyl (4-oxobenzo[d][1,2,3]triazin-3(4H)-yl) phosphate;3-(Diethoxy-phosphoryloxy)-1,2,3-benzo[d]triazin-4(3H)-one |
| CAS: | 165534-43-0 |
| MF: | C11H14N3O5P |
| MW: | 299.22 |
| EINECS: | 628-030-5 |
| Product Categories: | Antibiotics;Peptide Coupling Reagents;Coupling Reagent;Biochemistry;Condensation & Active Esterification;Coupling Reactions (Peptide Synthesis);Peptide Synthesis;Synthetic Organic Chemistry;Peptide;Building Blocks;Heterocyclic Building Blocks;Triazines |
| Mol File: | 165534-43-0.mol |
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DEPBT Chemical Properties
| Melting point | 75-77°C |
| Boiling point | 382.1±25.0 °C(Predicted) |
| density | 1.45±0.1 g/cm3(Predicted) |
| storage temp. | Store at +2°C to +8°C. |
| solubility | almost transparency in Ethylacetate |
| form | Powder |
| color | White |
| InChI | InChI=1S/C11H14N3O5P/c1-3-17-20(16,18-4-2)19-14-11(15)9-7-5-6-8-10(9)12-13-14/h5-8H,3-4H2,1-2H3 |
| InChIKey | AJDPNPAGZMZOMN-UHFFFAOYSA-N |
| SMILES | P(ON1C(=O)C2=CC=CC=C2N=N1)(OCC)(OCC)=O |
| CAS DataBase Reference | 165534-43-0(CAS DataBase Reference) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| HS Code | 29339990 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
DEPBT Usage And Synthesis
| Chemical Properties | White solid |
| Uses | DEPBT is a peptide coupling reagent used in peptide synthesis. It shows remarkable resistance to racemization. |
| General Description | 3-(Diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one (DEPBT) is a coupling reagent that facilitates amide bond formation and also resists racemization. It has been shown to be more effective than phosphonium and uronium coupling reagents. |
DEPBT Preparation Products And Raw materials
| Raw materials | 3-Hydroxy-1,2,3-benzotriazin-4(3H)-one-->Diethyl phosphite-->Diethyl chlorophosphate |
| Preparation Products | 1H-INDOL-1-AMINE |
