Introduction：Basic information about Dimethyldioctadecylammonium bromide CAS 3700-67-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Dimethyldioctadecylammonium bromide Basic information
| Product Name: | Dimethyldioctadecylammonium bromide |
| Synonyms: | DiMethyldioctadecylaMMoniuM (BroMide Salt);DIMETHYLDIOCTADECYLAMMONIUM (BROMIDE SALT);18:0 DDAB;DDA;DIMETHYLDIOCTADECYLAMMONIUM BROMIDE;DIMETHYL DI-N-OCTADECYLAMMONIUM BROMIDE;DIMETHYLDISTEARYLAMMONIUM BROMIDE;DISTEARYLDIMETHYLAMMONIUM BROMIDE;18:0 DDAB |
| CAS: | 3700-67-2 |
| MF: | C38H80BrN |
| MW: | 630.95 |
| EINECS: | 223-037-6 |
| Product Categories: | Ammonium Bromides (Quaternary);Quaternary Ammonium Compounds |
| Mol File: | 3700-67-2.mol |
|
Dimethyldioctadecylammonium bromide Chemical Properties
| Melting point | ~160 °C |
| density | 1.047 |
| refractive index | 1.5260 (estimate) |
| RTECS | RG0185984 |
| storage temp. | -20°C |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly, Heated), Hexanes (Slightly, Heated) |
| form | Granular Powder |
| color | White |
| BRN | 3580323 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| InChI | InChI=1S/C38H80N.BrH/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-39(3,4)38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2;/h5-38H2,1-4H3;1H/q+1;/p-1 |
| InChIKey | PSLWZOIUBRXAQW-UHFFFAOYSA-M |
| SMILES | C(CCCCCCCCCCCCCCCCC)[N+](C)(C)CCCCCCCCCCCCCCCCCC.[Br-] |
| CAS DataBase Reference | 3700-67-2(CAS DataBase Reference) |
| EPA Substance Registry System | 1-Octadecanaminium, N,N-dimethyl-N-octadecyl-, bromide (3700-67-2) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38-43 |
| Safety Statements | 26-37/39 |
| WGK Germany | 3 |
| TSCA | TSCA listed |
| HazardClass | 9 |
| HS Code | 29211990 |
| Storage Class | 11 - Combustible Solids |
Dimethyldioctadecylammonium bromide Usage And Synthesis
| Description | 18:0 DDAB is a double-chained quaternary ammonium surfactant with a bromide counter ion. |
| Chemical Properties | white powder |
| Uses | Dimethyldioctadecylammonium bromide has been used in a study to assess the interaction of its monolayers with DNA using specular neutron reflection, surface pressure-area isotherms, and Brewster angle microscopy. It has also been used in a study to investigate new adjuvants for use in kill vaccines for bovine viral diarrhea virus (BVDV). |
| General Description | 18:0 DDAB is cationic lipid and a quaternary ammonium salt. The hydrocarbon tails are saturated unlike the ionizable lipids. |
| Biochem/physiol Actions | 18:0 DDAB is a surface-active molecule, used as an adjuvant to induce systemic immune response. It is non-toxic. |
| Purification Methods | Crystallise the bromide from acetone, then MeOH [Lukac J Am Chem Soc 106 4387 1984]. Also purify it by chromatography on alumina by washing with *C6H6 and eluting with Me2CO, evaporating and crystallising from MeCN [Swain & Kreevoy J Am Chem Soc 77 1126 1955]. [Beilstein 4 IV 829.] |
Dimethyldioctadecylammonium bromide Preparation Products And Raw materials
| Raw materials | Dimethylamine-->1-Bromooctadecane |
