DL-METHIONINE METHYLSULFONIUM CHLORIDE CAS 3493-12-7

Introduction：Basic information about DL-METHIONINE METHYLSULFONIUM CHLORIDE CAS 3493-12-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

DL-METHIONINE METHYLSULFONIUM CHLORIDE Basic information

• Product Name: DL-METHIONINE METHYLSULFONIUM CHLORIDE
• Synonyms: VITAMIN U;VITAMIN U CHLORIDE;(3-amino-3-carboxypropyl)dimethyl-,chloride,(+/-)-sulfoniu;METHYL-METHIONINE SULPHONIUM CHLORIDE;DL-METHYLMETHIONINE SULFONIUMCHLORIDE;DL-METHIONINE METHYLSULFONIUM CHLORIDE;DL-(3-AMINO-3-CARBOXYPROPYL)DIMETHYLSULFONIUM CHLORIDE;CITRIN
• CAS: 3493-12-7
• MF: C6H14ClNO2S
• MW: 199.7
• EINECS: 222-484-4
• Product Categories: Vitamin series;Iodonium Sulfonium & Oxonium Compounds;Sulfonium Compounds
• Mol File: 3493-12-7.mol

DL-METHIONINE METHYLSULFONIUM CHLORIDE Chemical Properties

• Melting point: 139-140 °C (dec.)
• FEMA: 3445 | DL-(3-AMINO-3-CARBOXYPROPYL)DIMETHYLSULFONIUM CHLORIDE
• storage temp.: Inert atmosphere,Room Temperature
• solubility: H2O: soluble100mg/mL, clear, colorless
• form: Solid
• color: White to Off-White
• PH: 4.0-5.5
• biological source: synthetic
• Water Solubility: Water: 250 mg/mL (1251.88 mM)
• JECFA Number: 1427
• Merck: 14,6098
• BRN: 4163617
• Stability: Hygroscopic
• InChI: 1S/C6H13NO2S.ClH/c1-10(2)4-3-5(7)6(8)9;/h5H,3-4,7H2,1-2H3;1H
• InChIKey: MYGVPKMVGSXPCQ-UHFFFAOYSA-N
• SMILES: [Cl-].C[S+](C)CCC(N)C(O)=O
• CAS DataBase Reference: 3493-12-7(CAS DataBase Reference)
• EPA Substance Registry System: Sulfonium, (3-amino-3-carboxypropyl)dimethyl-, chloride (3493-12-7)

Safety Information

• Safety Statements: 24/25
• WGK Germany: 3
• TSCA: TSCA listed
• HS Code: 29309090
• Storage Class: 11 - Combustible Solids

DL-METHIONINE METHYLSULFONIUM CHLORIDE Usage And Synthesis

Description

DL-Methionine methylsulfonium chloride, also named Vitamin U, is a powerful antioxidant. It is a sulfur derivative substance. Graviola leaves contain much vitamin U[1]. Vitamin U have unique antioxidant effect. It could prevents Galactosamine-induced gastric damage and protects pentylenetetrazole-induced brain damage in rats[2-3].

Uses

DL-Methionine Methylsulfonium Chloride is a compound comprised of γ-glutamyl peptide and amino acid that have a sucrose-like taste.

Uses

Vitamin U (DL-methionine methylsulfoniumchloride) is a natural methionine-derivative,found as an active component in themethionine cycle of plants where it serves asa substrate for methyl transferases(Augspurger et al., 2005). Historically thiscompound has been utilized as either a cure or preventative against gastric and duodenalulcers (Nakamura et al., 1981).

Biochem/physiol Actions

S-Methionine methylsulfonium (SMMS) chloride is a derivative of methionine metabolism in some plants. SMMS has potent therapeutic effects on gastrointestinal ulceration potentially via its ability to promote dermal fibroblast migration and growth.

References

[1] Choi E, et al. Increased Intestinal Absorption of Vitamin U in Steamed Graviola Leaf Extract Activates Nicotine Detoxification. Nutrients, 2019; 11.
[2] Topaloglu D, et al. Gastroprotective effect of vitamin U in D-galactosamine-induced hepatotoxicity. Journal of Biochemical and Molecular Toxicology, 2022; 36: e23124.
[3] Bayrak G, et al. The protective effect of vitamin U on pentylenetetrazole-induced brain damage in rats, 2022; 36: e23169.