Introduction：Basic information about DL-Valine CAS 516-06-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
DL-Valine Basic information
| Product Name: | DL-Valine |
| Synonyms: | Valine, DL-;H-DL-VAL-OH;FEMA 3444;DL-VAL;(±)-α-Aminoisovaleric acid, DL-2-Amino-3-methylbutanoic acid;(R,S)-2-Amino-3-methyl-butyricacid;DL-alpha-Aminoisovaleric acid;DL-α-Aminoisovaleric acid |
| CAS: | 516-06-3 |
| MF: | C5H11NO2 |
| MW: | 117.15 |
| EINECS: | 208-220-0 |
| Product Categories: | Valine [Val, V];alpha-Amino Acids;Amino Acids;Biochemistry;Amino Acids |
| Mol File: | 516-06-3.mol |
|
DL-Valine Chemical Properties
| Melting point | 295 °C (dec.) (lit.) |
| alpha | -0.6～+0.6° (20℃/D)(c=8, HCl) |
| Boiling point | 213.6±23.0 °C(Predicted) |
| density | 1.31 |
| FEMA | 3444 | D,L-VALINE |
| refractive index | 1.4650 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Water (Slightly, Sonicated) |
| pka | pK1:2.32(+1);pK2:9.61(0) (25°C) |
| form | Crystalline Powder |
| color | White |
| Odor | Odorless |
| Odor Type | odorless |
| biological source | synthetic |
| Water Solubility | 68 g/L |
| Merck | 14,9909 |
| JECFA Number | 1426 |
| BRN | 506689 |
| Major Application | flavors and fragrances |
| Cosmetics Ingredients Functions | SKIN CONDITIONING
FRAGRANCE
ANTISTATIC
HAIR CONDITIONING |
| InChI | 1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8) |
| InChIKey | KZSNJWFQEVHDMF-UHFFFAOYSA-N |
| SMILES | CC(C)C(N)C(O)=O |
| LogP | 0.29 |
| CAS DataBase Reference | 516-06-3(CAS DataBase Reference) |
| NIST Chemistry Reference | DL-Valine(516-06-3) |
| EPA Substance Registry System | Valine (516-06-3) |
Safety Information
| Hazard Codes | Xn |
| Risk Statements | 40 |
| Safety Statements | 22-24/25-36 |
| WGK Germany | 3 |
| RTECS | YV9355500 |
| TSCA | TSCA listed |
| HS Code | 29224995 |
| Storage Class | 11 - Combustible Solids |
DL-Valine Usage And Synthesis
| Chemical Properties | White crystalline powder |
| Chemical Properties | dl-Valine is odorless. |
| Occurrence | Reported found in many fruits, plants and animal tissues; in milk and dairy products. |
| Uses | peptide synthesis |
| Preparation | By the action of ammonia on α-bromoisovaleric acid; also through a hydantoin intermediate. |
| Definition | ChEBI: A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isopropyl group. |
| reaction suitability | reaction type: solution phase peptide synthesis |
DL-Valine Preparation Products And Raw materials
| Raw materials | POTASSIUM CYANIDE-->Isobutyraldehyde-->Nalidixic acid |
| Preparation Products | L-Valine-->D-Valine-->D-2-AMINO-1,1,1-TRIFLUORO-3-(METHYL)BUTANE-->1-MethoxyMethyl-2-Methyl-propylaMine-->Valaciclovir-->2-methanesulfonamido-3-methylbutanoic acid-->FMoc-DL-valine-->methyl 2-isocyanato-3-methylbutanoate-->Valine, N-(2-phenylacetyl)--->2-(4-FLUORO-BENZOYLAMINO)-3-METHYL-BUTYRIC ACID-->2-(4-FLUOROBENZENESULPHAMIDO)-3-METHYLBUTYRIC ACI-->2-[(FURAN-2-CARBONYL)-AMINO]-3-METHYL-BUTYRIC ACID-->3-methyl-2-(4-oxo-2-thioxothiazolidin-3-yl)butanoic acid-->VALINE BENZYL ESTER |
