CAS 16063-80-2|4,4,4,4',4',4'-Hexafluoro-DL-valine
Introduction：Basic information about CAS 16063-80-2|4,4,4,4',4',4'-Hexafluoro-DL-valine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
4,4,4,4',4',4'-Hexafluoro-DL-valine is a valine derivative[1].
Related Catalog
Research Areas >>OthersSignaling Pathways >>Others >>Others
In Vitro
Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References
[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.
Chemical & Physical Properties
Density
1.575 g/cm3
Boiling Point
165.9ºC at 760 mmHg
Melting Point
204°C (dec.)
Molecular Formula
C5H5F6NO2
Molecular Weight
225.08900
Flash Point
54.1ºC
Exact Mass
225.02200
PSA
63.32000
LogP
1.83940
Index of Refraction
1.349
InChIKey
KRNSHCKTGFAMPQ-UHFFFAOYSA-N
SMILES
NC(C(=O)O)C(C(F)(F)F)C(F)(F)F
Safety Information
Hazard Codes
Xi: Irritant;
Safety Phrases
S22-S24/25
RIDADR
UN3335
HS Code
2922499990
Customs
HS Code
2922499990
Summary
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%
Articles2
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Synthesis of fluorine-containing peptides. Analogues of angiotensin II containing hexafluorovaline.
J. Med. Chem. 24(9) , 1043-7, (1981)
Gamma, gammma, gammma, gammma', gamma', gammma'-Hexafluorovaline and derivatives have been prepared and incorporated into angiotensin II by fragment condensation and solid-phase peptide synthesis. Hex...
Long-acting angiotensin II inhibitors containing hexafluorovaline in position 8.
J. Med. Chem. 30(6) , 1097-100, (1987)
An improved synthesis of hexafluorovaline (Hfv) derivatives, i.e., DL-Hfv-OBzl and Boc-DL-Hfv, is described. Incorporation of hexafluorovaline into angiotensin resulted in [Sar1,Hfv8]AII and [Sar1,D-H...
