Introduction：Basic information about Dulcitol CAS 608-66-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Dulcitol Basic information
| Product Name: | Dulcitol |
| Synonyms: | DAG;D-Dulcitol;Dulcose;Euonymit;Melampyrin;Melampyrit;Melampyrum;DOXYCYCLINE MONOHYDRATE |
| CAS: | 608-66-2 |
| MF: | C6H14O6 |
| MW: | 182.17 |
| EINECS: | 210-165-2 |
| Product Categories: | Carbohydrates & Derivatives, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;carbohydrate;Biochemistry;Galactose;Sugar Alcohols;Sugars;Dextrins、Sugar & Carbohydrates;Miscellaneous Natural Products |
| Mol File: | 608-66-2.mol |
|
Dulcitol Chemical Properties
| Melting point | 98-100 °C(lit.) |
| Boiling point | 275-280°C (1 mmHg) |
| density | 1.28 g/mL at 25 °C |
| vapor density | <1 (vs air) |
| vapor pressure | <0.1 mm Hg ( 25 °C) |
| refractive index | n20/D 1.46 |
| Fp | 275-280°C/1mm |
| storage temp. | 2-8°C |
| solubility | H2O: 1 M at 20 °C, clear, colorless |
| form | liquid |
| pka | pKa 13.57(H2Ot = 18t = 0)(Approximate);14.14(H2Ot = 18t = 0)(Approximate) |
| color | White to Off-white |
| Odor | Odorless. |
| PH | 6.0-6.5 (50g/l, H2O, 20℃) |
| Water Solubility | SOLUBLE IN HOT WATER |
| Sensitive | Hygroscopic |
| Merck | 14,4332 |
| BRN | 1721903 |
| Major Application | pharmaceutical (small molecule) |
| InChI | 1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5+,6- |
| InChIKey | FBPFZTCFMRRESA-GUCUJZIJSA-N |
| SMILES | OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)CO |
| LogP | -3.100 |
| CAS DataBase Reference | 608-66-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Galactitol(608-66-2) |
| EPA Substance Registry System | Galactitol (608-66-2) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 8-24/25-36/37-26 |
| WGK Germany | 2 |
| RTECS | LZ4290000 |
| F | 3 |
| TSCA | TSCA listed |
| HS Code | 29054990 |
| Storage Class | 11 - Combustible Solids |
Dulcitol Usage And Synthesis
| Chemical Properties | Crystalline |
| Chemical Properties | The solubility of D-sorbitol (D-glucitol, is D-glucohexan-1.2.3.4.5.6-hexaol) inwater is up to approximately 2,350 g/L at room temperature. Sorbitol is stableunder the common processing conditions of foods. In addition to the dry sorbitol,syrups are available.
Sorbitol is, depending on the concentration, approximately 60 % as sweet assucrose and noncariogenic.
In the European Union, sorbitol is approved as E 420 for a large number of foodapplications, in the United States as GRAS, and is also approved in many othercountries.
Sorbitol is generally produced by chemical hydrogenation of glucose or,together with mannitol, by chemical hydrogenation of fructose. |
| Uses | Dulcitol is important in studies related to cataract formation, hepatosplenμly and mental retardation. It is used as a substrate to identify, differentiate and characterize galactitol dehydrogenase(s). It is also used as a reference compound in analytical procedures developed to analyze sugar alcohols in plants and food. |
| Uses | Dulcitol is the reduction product of Galactose. An increase in the level of Dulcitol is often a result of metabolism defect caused by a defect in galactose-1-phosphate uridylyltransferase (an autosomal recessive disorder). Dulcitol buildup can also lead t |
| Uses | sorbitol absorbs moisture from the air to prevent skin dryness, and leaves the skin feeling smooth and velvety. However, if the skin’s moisture content is greater than that of the atmosphere, it will draw moisture out of the skin, thereby increasing the feeling of dryness. Sorbitol is used by formulators as a replacement for glycerin in emulsions, ointments, and various cosmetic creams. It is obtained from the leaves and in some cases the berries of mountain ash. Sorbitol also occurs in other berries, cherries, plums, pears, apples, seaweed, and algae. |
| Definition | ChEBI: An optically inactive hexitol having meso-configuration. |
| Brand name | Sorbo (ICI Americas). |
| General Description | Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards |
| Health Hazard | Recommended Personal Protective Equipment: Goggles or face shield; protective clothing for hot liquid; Symptoms Following Exposure: Hot liquid will burn skin; General Treatment for Exposure: Only for burns caused by hot liquid; Toxicity by Inhalation (Threshold Limit Value): Not pertinent; Short-Term Inhalation Limits: Not pertinent; Toxicity by Ingestion: None; Late Toxicity: None; Vapor (Gas) Irritant Characteristics: Nonvolatile; Liquid or Solid Irritant Characteristics: Data not available; Odor Threshold: Not pertinent. |
| Chemical Reactivity | Reactivity with Water No reaction; Reactivity with Common Materials: No reactions; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent. |
| Biochem/physiol Actions | A sugar alcohol and slightly sweet tastant for human taste cells. |
Dulcitol Preparation Products And Raw materials
| Raw materials | Sodium borohydride-->D-GALACTOSE 1-[2-(2-AZIDOETHOXY)ETHOXYETHYL]-2,3,4,6-TETRA-O-ACETATE |
| Preparation Products | .beta.-D-Galactopyranose-->Furfural |
