Introduction：Basic information about DYCLONINE CAS 586-60-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
DYCLONINE Basic information
| Product Name: | DYCLONINE |
| Synonyms: | DYCLONINE;1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanon;4’-butoxy-3-piperidino-propiophenon;dyclocaine;dyclonin;4'-Butoxy-β-piperidinopropiophenone;Dyclonine HCI;1-(4-butoxyphenyl)-3-(piperidin-1-yl)propan-1-one |
| CAS: | 586-60-7 |
| MF: | C18H27NO2 |
| MW: | 289.41 |
| EINECS: | 1312995-182-4 |
| Product Categories: | DYCLONE |
| Mol File: | 586-60-7.mol |
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DYCLONINE Chemical Properties
| Boiling point | 424.5±25.0 °C(Predicted) |
| density | 1.017±0.06 g/cm3(Predicted) |
| pka | 8.68±0.10(Predicted) |
Safety Information
DYCLONINE Usage And Synthesis
| Originator | Dyclone,Dow,US,1956 |
| Uses | anesthetic (local) |
| Definition | ChEBI: N-Ethylpiperidine in which one of the hydrogens attached to the methyl group is substituted by a 4-butoxybenzoyl group. |
| Manufacturing Process | A mixture of 17.6 grams of p-n-butoxyacetophenone, 12.1 grams of piperidinehydrochloride, 4.5 grams paraformaldehyde, 0.25 cc concentrated hydrochloricacid, 52.5 cc nitroethane, 7.5 cc of 95% ethanol, and 15 cc of toluene wasboiled under reflux for one hour, removing water formed in the reaction bymeans of a condensate trap. The mixture was then cooled. The crystals whichformed were collected by filtration, washed with anhydrous ether andrecrystallized from methyl ethyl ketone. The crystals thus obtained, whichmelted at 174-175°C, were shown by analysis to be 4-n-butoxy-β-piperidinopropiophenone hydrochloride. |
| Brand name | Dyclone (AstraZeneca). |
| Therapeutic Function | Local anesthetic |
DYCLONINE Preparation Products And Raw materials
| Raw materials | Hydrochloric acid-->Piperidine hydrochloride-->Paraformaldehyde |
