E3 Ligase Ligand-Linker Conjugates 24 (TFA) CAS 1957235-75-4

Introduction：Basic information about E3 Ligase Ligand-Linker Conjugates 24 (TFA) CAS 1957235-75-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

E3 Ligase Ligand-Linker Conjugates 24 (TFA) Basic information

• Product Name: E3 Ligase Ligand-Linker Conjugates 24 (TFA)
• Synonyms: E3 Ligase Ligand-Linker Conjugates 24 (TFA);Thalidomide-O-amido-PEG2-C2-NH2 TFA;Cereblon Ligand-Linker Conjugates 10 TFA;Thalidomide-O-amido-PEG2-NH2.TFA;Thalidomide O amido PEG2 C2 NH2 TFA,Cereblon Ligand-Linker Conjugates 10,E3 Ligase Ligand-Linker Conjugates 24,Inhibitor,inhibit,Thalidomide-O-amido-PEG-2-C2-NH2 TFA,ThalidomideOamidoPEG2C2NH2 TFA,E3 Ligase Ligand-Linker Conjugates;Acetamide,?N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-, 2,2,2-trifluoroacetate (1:1)
• CAS: 1957235-75-4
• MF: C23H27F3N4O10
• MW: 576.48
• Product Categories: peg
• Mol File: 1957235-75-4.mol

E3 Ligase Ligand-Linker Conjugates 24 (TFA) Chemical Properties

• storage temp.: 2-8°C, sealed storage, away from moisture
• form: Solid
• color: White to light yellow

E3 Ligase Ligand-Linker Conjugates 24 (TFA) Usage And Synthesis

Uses

Thalidomide-O-amido-PEG2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.

IC 50

Cereblon

References

[1] ARYL SULFONOHYDRAZIDES. WO 2017/176958 A1.