Introduction：Basic information about EC 1.1.1.37 CAS 9001-64-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
EC 1.1.1.37 Basic informationDescription Source Background
| Product Name: | EC 1.1.1.37 |
| Synonyms: | (S)-MALATE : NAD+ OXIDOREDUCTASE;MDH;MDH MITOCHONDRIAL;MALATE DEHYDROGENASE;MALATE DEHYDROGENASE, HUMAN HEART, CYTOPLASMA;MALATE DEHYDROGENASE, HUMAN HEART, MITOCHONDRIA;MALATE DEHYDROGENASE MITOCHONDRIAL;MALATE DEHYDROGENASE PORCINE HEART |
| CAS: | 9001-64-3 |
| MF: | NULL |
| MW: | 0 |
| EINECS: | 232-622-5 |
| Product Categories: | enzyme;Enzymes;Elisa Kit-plant ELISA Kit |
| Mol File: | Mol File |
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EC 1.1.1.37 Chemical Properties
| storage temp. | 2-8°C |
| solubility | 0.1 M phosphate buffer: 5mg/mL |
| form | suspension |
| color | slightly beige |
| biological source | Porcine heart |
| Specific Activity | 600-1000units/mg protein (biuret) |
| CAS DataBase Reference | 9001-64-3 |
| EPA Substance Registry System | Dehydrogenase, malate (9001-64-3) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 22-24/25-36-26 |
| WGK Germany | 3 |
| TSCA | TSCA listed |
| HS Code | 35079090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 |
EC 1.1.1.37 Usage And Synthesis
| Chemical Properties | Powder |
| Uses | Malic dehydrogenase has been used in a study to assess a flow injection system for on-line monitoring of fumaric acid in biological processes. It has also been used in a study to investigate a root-knot nematode parasitizing peanut in Texas. |
| Uses | Malic dehydrogenase has been used in a study to assess the comparative molluscicidal action of Ginko biloba extract on snail hosts. It has also been used in a study to investigate the effect of early feed restriction on metabolic programming and compensatory growth in broiler chickens. |
| General Description | Cytoplasmic Isozyme |
| Biochem/physiol Actions | Malic Dehydrogenase (MDH) plays an important role in the citric acid cycle in mitochondria. It catalyzes the interconversion of substrates malate and oxaloacetate with the simultaneous oxidation/reduction of NAD/NADH+. MDH present in the cytosol is involved in the shuttling of malate/aspartate. |
| Description | MDH2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 335 amino acids (25-338 a.a.) and having a molecular mass of 35.2 kDa. The MDH2 is fused to a 21 amino acid His tag at N-terminus and purified by conventional chromatography. |
| Source | Escherichia Coli |
| Background | MDH2 catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. MDH2 is localized to the mitochondria and takes part in the malate-aspartate shuttle that functions in the metabolic coordination between cytosol and mitochondria. MDH2 is highy expressed in the adrenal system, small intestine, heart and pancreas. |
EC 1.1.1.37 Preparation Products And Raw materials
