Introduction：Basic information about EPINASTINE HYDROCHLORIDE CAS 108929-04-0, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
EPINASTINE HYDROCHLORIDE Basic information
| Product Name: | EPINASTINE HYDROCHLORIDE |
| Synonyms: | f)imidazo(1,5-a)azepin-3-amine,9,13b-dihydro-ih-dibenz(hydrochloride;EPINASTINE HCL;EPINASTIN HCL;3-AMINO-9,13B-DIHYDRO-1H-DIBENZ[C,F]IMIDAZO[1,5-A]AZEPINE HYDROCHLORIDE;WAL-801CL;9,13b-Dihydro-1H-Dibenz[c,f]imidazo[1,5-α]azepin-3-amine Hydrochloride;Alesion;Elestat |
| CAS: | 108929-04-0 |
| MF: | C16H16ClN3 |
| MW: | 285.77 |
| EINECS: | 629-843-8 |
| Product Categories: | Inhibitors;Heterocyclic Compounds;Bases & Related Reagents;Heterocycles;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Antihistaminic |
| Mol File: | 108929-04-0.mol |
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EPINASTINE HYDROCHLORIDE Chemical Properties
| Melting point | 273-275°C |
| storage temp. | 2-8°C |
| solubility | H2O: soluble38mg/mL |
| form | solid |
| color | white |
| InChI | 1S/C16H15N3.ClH/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16;/h1-8,15H,9-10H2,(H2,17,18);1H |
| InChIKey | VKXSGUIOOQPGAF-UHFFFAOYSA-N |
| SMILES | Cl[H].NC1=NCC2N1c3ccccc3Cc4ccccc24 |
Safety Information
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | HO4360000 |
| HS Code | 2933992600 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 3 Oral |
| Toxicity | LD50 in male, female rats (mg/kg): 314, 192 orally; 17, 22 i.v. (Nishikawa) |
EPINASTINE HYDROCHLORIDE Usage And Synthesis
| Chemical Properties | White Crystalline Solid |
| Uses | A tetracyclic, non-sedating histamine H1 receptor antagonist. Antihistaminic. |
| Biochem/physiol Actions | Epinastine hydrochloride is a non-sedating H1 histamine receptor antagonist. |
EPINASTINE HYDROCHLORIDE Preparation Products And Raw materials
| Raw materials | 11H-Dibenz[b,e]azepine, 6-chloro--->6-Aminomethyl-5,6-dihydromorphanthridine-->N-[2-(Phenylmethyl)phenyl]-2-chloroacetamide-->11H-Dibenzo[b,e]azepine-6-carbonitrile-->Epinastine-->2-Benzylaniline-->Cyanogen bromide-->2-Aminobenzophenone |
