Introduction：Basic information about Flavomycin CAS 11015-37-5, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Flavomycin Basic information
| Product Name: | Flavomycin |
| Synonyms: | BAMBERMYCIN;BAMBERMYCINS;flavophospholipol;FLAVOMYCIN;MOENOMYCIN;moenomycin a;Flavomycin Premix;menomycin |
| CAS: | 11015-37-5 |
| MF: | C69H107N4O35P |
| MW: | 1583.57 |
| EINECS: | 234-246-7 |
| Product Categories: | |
| Mol File: | 11015-37-5.mol |
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Flavomycin Chemical Properties
| Melting point | >150° (dec.) |
| storage temp. | 0-6°C |
| solubility | Water (Slightly) |
| form | Solid |
| color | Dark Brown |
| InChIKey | PERZMHJGZKHNGU-XIGAONJHSA-N |
| LogP | 1.983 (est) |
| CAS DataBase Reference | 11015-37-5 |
| EPA Substance Registry System | Bambermycin (11015-37-5) |
Safety Information
| Risk Statements | 53 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | 1 |
| RTECS | QA3020000 |
| Toxicity | LD50 in mice (mg/kg): >2000 orally, s.c. and i.p.; 1400 i.v. (Lindner, Wallhuser) |
Flavomycin Usage And Synthesis
| Description | Moenomycin complex is a mixture of moenomycins A, A12, C1, C3 and C4, which are antibiotics isolated from several strains of Streptomyces that directly inhibit bacterial peptidoglycan glycosyltransferases. The minimal inhibitory concentration of moenomycin A against various Gram-positive bacteria ranges from 1-100 nM. |
| Chemical Properties | Colorless amorphous salt, right 4 kinds of microbial active substances with similar chemical properties composed of stable complexes, containing phosphorus 1.96%, weak acid. Soluble in water and low molecular alcohol, insoluble in other organic solvents. |
| Uses | Moenomycin complex is an antibiotic and selective inhibitor of the transglycosylation step. Flavomycin (bambermycins) is an antibiotic complex obtained from Streptomyces bambergiensis containing mainly Moenomycins A and C. They are used as feed additives and growth promoters for swine, poultry and cattle. |
| Uses | Moenomycin complex is a mixture of five major components, A, A12, C1, C3 and C4, isolated from several strains of Streptomyces in the 1960s. Moenomycins are high molecular weight phosphoglycolipids with potent antibiotic activity used in animal health. Moenomycins are the only antibiotic known to selectively inhibit the transglycosylation step catalysed by penicillin-binding protein 1b. |
| Definition | ChEBI: A glycophospholipid antibiotic compound with the lipid portion conjugated to a pentasaccharide fraction via a phosphate linkage. |
| Brand name | Flavomycin (Hoechst-Roussel). |
| General Description | Flavophospholipol, formerly called moenomycin, was found in the culture broth of Streptomyces bambergiensis by Hoechst in 1955. This drug is called bambermycin by INN and in the United States. It shows strong activity against gram-positive bacteria and weak activity against gram-negative bacteria. Flavophospholipol has been used as a feed additive for growth promotion in poultry. |
| Safety Profile | Poison by intravenousroute. Moderately toxic by subcutaneousroute. |
| References | [1] OSTASH B, WALKER S. Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity[J]. Natural Product Reports, 2010, 11: 1594-1617. DOI: 10.1039/c001461n |
Flavomycin Preparation Products And Raw materials
| Raw materials | Soy bean Isoflavone Isoflavone 10-40% |
