Introduction：Basic information about Ginsenoside Rh1 CAS 63223-86-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Ginsenoside Rh1 Basic information
| Product Name: | Ginsenoside Rh1 |
| Synonyms: | sanchinoside rh1;(3beta,6alpha,12beta)-3,12,20-trihydroxydammar-24-en-6-yl?beta-d-glucopyranoside;Ginsenoside Rh1 (Prosapogenin A2;GINSENOSIDE RH1;(20S)-6α-(β-D-Glucopyranosyloxy)-3β,12β,20-trihydroxydammara-24-ene;(20S)-6α-(β-D-Glucopyranosyloxy)dammar-24-ene-3β,12β,20-triol;3β,12β,20-Trihydroxy-5α-dammar-24-en-6α-yl β-D-glucopyranoside;6α-(β-D-Glucopyranosyloxy)-dammara-24-ene-3β,12β,20-triol |
| CAS: | 63223-86-9 |
| MF: | C36H62O9 |
| MW: | 638.88 |
| EINECS: | |
| Product Categories: | Ginsenoside series;Inhibitors;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract |
| Mol File: | 63223-86-9.mol |
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Ginsenoside Rh1 Chemical Properties
| Boiling point | 755.1±60.0 °C(Predicted) |
| density | 1.23 |
| storage temp. | 2-8°C |
| solubility | DMSO : 100 mg/mL (156.53 mM; Need ultrasonic) |
| form | powder |
| pka | 12.91±0.70(Predicted) |
| color | White |
| Major Application | food and beverages |
| Cosmetics Ingredients Functions | HAIR CONDITIONING
SKIN CONDITIONING - HUMECTANT |
| InChIKey | RAQNTCRNSXYLAH-CCJJTDGONA-N |
| SMILES | C\C(C)=C/CC[C@](C)(O)[C@H]1CC[C@]2(C)[C@@H]1[C@H](O)C[C@@H]3[C@@]4(C)CC[C@H](O)C(C)(C)[C@@H]4[C@H](C[C@@]23C)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O |
| LogP | 3.740 (est) |
Safety Information
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral |
Ginsenoside Rh1 Usage And Synthesis
| Chemical Properties | White powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from ginseng. |
| Uses | 20(S)?-?Ginsenoside Rh1 is an anti-cancer agent found in the leaves of ginseng. |
| Definition | ChEBI: (20S)-ginsenoside Rh1 is a tetracyclic triterpenoid that is (20S)-protopanaxadiol which is substituted by beta-D-glucoside at the 6alpha position. It has a role as a plant metabolite. It is a beta-D-glucoside, a 12beta-hydroxy steroid, a tetracyclic triterpenoid, a ginsenoside, a 3beta-hydroxy steroid and a 3beta-hydroxy-4,4-dimethylsteroid. It derives from a hydride of a dammarane. |
| in vivo | When high-fat diet (HFD) fed mice for 8 weeks, body and epididymal fat weight gains are significantly increased compared to those of low-fat diet (LFD)-fed mice. However, when Ginsenoside Rh1 is treated in HFD-fed mice, body and epididymal fat weight gains are significantly decrease compared with those of the HFD-fed mice. TG, glucose, insulin, total cholesterol, and HDL levels in the blood are significantly increased in HFD-fed mice group compared to LFD-fed mice group. Treatment with Ginsenoside Rh1 in HFD-fed mice significantly lowers TG level alone[1]. |
| IC 50 | PPAR-γ; IL-6; IL-1β |
Ginsenoside Rh1 Preparation Products And Raw materials
