Guar gum CAS 9000-30-0
Introduction：Basic information about Guar gum CAS 9000-30-0, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Guar gum Basic informationChemical Properties Uses
| Product Name: | Guar gum |
| Synonyms: | Guar GuM Hydrolyzed;Guar Gum - HPMC;1212a;a-20d;burtonitev7e;burtonitev-7-e;cyamopsisgum;dealcatp1 |
| CAS: | 9000-30-0 |
| MF: | C10H14N5Na2O12P3 |
| MW: | 535.145283 |
| EINECS: | 232-536-8 |
| Product Categories: | thickener;Pharmaceutical intermediates;9000-30-0 |
| Mol File: | 9000-30-0.mol |
Guar gum Chemical Properties
| Melting point | >220°C (dec.) |
| alpha | D25 +53° (1N NaOH) |
| density | 0.8-1.0 g/cm3 |
| FEMA | 2537 | GUAR GUM (CYAMOPSIS TETRAGONOLOBUS (L.)) |
| refractive index | 1.34 |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | It yields a mucilage of variable viscosity when dissolved in water, practically insoluble in ethanol (96 per cent). |
| form | Free Flowing Powder |
| color | Yellow-white |
| Odor | Odorless |
| PH | 5.0-7.0 (25°C1% in water) |
| Merck | 13,4588 / 13,4587 |
| Stability: | Stable. Combustible. A mixture of air and finely-divided powder is potentially explosive. Incompatible with strong oxidizing agents. |
| Cosmetics Ingredients Functions | FILM FORMING BINDING FRAGRANCE SKIN CONDITIONING VISCOSITY CONTROLLING EMULSION STABILISING ANTIOXIDANT |
| Cosmetic Ingredient Review (CIR) | Guar gum (9000-30-0) |
| InChIKey | JEKDCIBJADJZSK-UHFFFAOYSA-L |
| SMILES | P(=O)(O[H])(OP(=O)([O-])OP(=O)([O-])O[H])OC([H])([H])C1([H])C([H])(C([H])([H])C([H])(N2C([H])=NC3=C(N([H])[H])N=C([H])N=C23)O1)O[H].[Na+].[Na+] |
| EPA Substance Registry System | Guar gum (9000-30-0) |
Safety Information
| WGK Germany | 1 |
| RTECS | MG0185000 |
| TSCA | TSCA listed |
| HS Code | 1302.39.0090 |
| Storage Class | 11 - Combustible Solids |
| Hazardous Substances Data | 9000-30-0(Hazardous Substances Data) |
| Toxicity | LD50 in male, female rats (g/kg): 7.35, 6.77 orally (Graham) |
| Chemical Properties | White to light yellowish.Free flowing powder.Close to odorless.Form viscous liquid after dispersing in hot or cold water. The viscosity of 1% aqueous solution is about 4~5Pa which is the highest viscosity in natural rubber. After adding small amount of sodium tetraborate it changes to gel. After dispersing in cold water for about 2h it shows strong viscosity and the viscosity gradually increases reached the highest point after 24h.Its viscosity is 5 to 8 times than that of starch and quickly reaches the highest point under heat.The aqueous solution is neutral.The viscosity is highest with pH between 6 and 8 and substantially decreases when pH is above10. And viscosity decreases sharply along with pH value dropping when pH value is 6.0 to 3.5. The viscosity below 3.5 increases again. | ||||||||||||||||||||||
| Uses |
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| Description | Background. Guar gum, like locust bean gum, is a galactomannanderived from the seed of a leguminous plant. The source of guar, Cyamopsis tetragonolobus, is widely grown in Pakistan and India as cattle feed, and was introduced to the United States as a cover crop in 1903. The U.S. is now also a producer. It was not until 1953, however, that guar gum was produced on a commercial scale, primarily as a replacement for locus bean gum in the paper, textile and food industries. The most important property of guar is the ability to hydrate rapidly in cold water to attain a very high viscosity. In addition to the food industry, guar is used in the mining, paper, textile, ceramic, paint, cosmetic, pharmaceutical, explosive, and other industries. Sources, Harvesting, and Producing Areas. The guar is a hardy and drought-resistant plant which grows three to six feet high with vertical stalks. The guar pods, which grow in clusters along the vertical stems, are about six inches long and contain 6 to 9 seeds, which are considerably smaller than locus bean seeds. As in the case of locust bean gum, the endosperm, which comprises 35-42%. | ||||||||||||||||||||||
| Chemical Properties | Guar gum is the endosperm of the seed of the Indian cluster bean, Cyamopsis tetragonolobus. It has been grown for several thousand years in India and Pakistan as a vegetable and a forage crop. The guar is a hardy and drought-resistant plant, which grows 1 to 2 m high with vertical stalks and resembles the soybean plant in general appearance. The guar pods, which grow in clusters along the vertical stems, are about 30 cm long and contain six to nine seeds, which are considerably smaller than locust bean seeds Guar gum is odorless. As in the case of locust bean gum, the endosperm, which comprises 35 to 42% of the seed, is the source of the gum Typically, guar gum is around 80% of the endosperm of the guar seed. As the endosperm is about 40% of the seed, guar gum is roughly 30% of the guar plant seed. It is harvested before the frst rain following the frst frost to obtain maximum yield and purity (Burdock, 1997). | ||||||||||||||||||||||
| Chemical Properties | The USP32–NF27 describes guar gum as a gum obtained from theground endosperms of Cyamopsis tetragonolobus (L.) Taub. (Fam.Leguminosae). It consists chiefly of a high-molecular-weighthydrocolloidal polysaccharide, composed of galactan and mannanunits combined through glycoside linkages, which may be describedchemically as a galactomannan. The PhEur 6.3 similarly describesguar galactomannan as being obtained from the seeds of Cyamopsistetragonolobus (L.) Taub. by grinding the endosperms andsubsequent partial hydrolysis. The main components are polysaccharides composed of Dgalactoseand D-mannose in molecular ratios of 1 : 1.4 to 1 : 2. Themolecule consists of a linear chain of b-(1!4)-glycosidically linkedmanno-pyranoses and single a-(1→6)-glycosidically linked galactopyranoses. Guar gum occurs as an odorless or nearly odorless, white toyellowish-white powder with a bland taste. | ||||||||||||||||||||||
| Chemical Properties | Yellowish-white free-flowing powder.Completely soluble in hot or cold water. Practicallyinsoluble in oils, greases, hydrocarbons, ketones,esters. Water solutions are tasteless, odorless, nontoxic.Has 5-8 times the thickening power of starch.Reduces the friction drag of water on metals. | ||||||||||||||||||||||
| Physical properties | Guar gum is a white to yellowish-white powder It is dispersible in either hot or cold water, forming a solution having a pH between 5.4 and 7.0 that may be converted to gel by the addition of a small amount of sodium borate. | ||||||||||||||||||||||
| Occurrence | Guar gum is an annual found in India, the United States, and the tropics of Asia. | ||||||||||||||||||||||
| Uses | guar gum has a coating action on the skin that allows for moisture retention. often used as a thickener and emulsifier in cosmetic formulations, guar gum is a polysaccharide found in the seeds of the guar plant. It is the nutrient material required by the developing plant embryo during germination. When the endosperm, once separated from the hull and embryo, is ground to a powder form, it is marketed as guar gum. | ||||||||||||||||||||||
| Uses | Guar gum is obtained from the seed kernel of the plant cyamopsis tetragonoloba. It has a mannose:galactose ratio of approximately 2:1. It is dispersible in cold water to form viscous sols which upon heating will develop additional viscosity. A 1% solution has a viscosity range of 2,000–3,500 cp at 25°c. It is a versatile thickener and stabilizer used in ice cream, baked goods, sauces, and beverages at use levels ranging from 0.1 to 1.0%. It is scientifically termed guaran. | ||||||||||||||||||||||
| Uses | low calorie, soluble dietery fiber | ||||||||||||||||||||||
| Uses | In paper sizing; as a protective colloid, stabilizer, thickening and film forming agent for cheese, salad dressings, ice cream, soups; as a binding and disintegrating agent in tablet formulations; in pharmaceutical jelly formulations; in suspensions, emulsions, lotions, creams, toothpastes; in the mining industry as a flocculant, as a filtering agent; in water treatment as a coagulant aid. Food additives, emulsifying stabilizer, thickener and gelling agent. | ||||||||||||||||||||||
| Definition | A water-soluble plant mucilage obtained from the ground endosperms of Cyanopsis tetragonoloba,cultivated in India and Pakistan as livestock feed, as well as in southwestern U.S. The water-soluble portion of the flour (85%) is called guaran and consists o | ||||||||||||||||||||||
| Production Methods | Guar gum is obtained from the ground endosperm of the guar plant,Cyamopsis tetragonolobus (L.) Taub. (Fam. Leguminosae), which isgrown in India, Pakistan, and the semiarid southwestern region ofthe USA. The seed hull can be removed by grinding, after soaking insulfuric acid or water, or by charring. The embryo (germ) isremoved by differential grinding, since each component possesses adifferent hardness. The separated endosperm, containing 80%galactomannan is then ground to different particle sizes dependingupon final application. | ||||||||||||||||||||||
| General Description | Off-white to yellowish-white powder. Five to eight times the thickening power of starch. Water solutions are tasteless, odorless, and nontoxic and have a pale translucent gray color with neutral pH. Water solutions converted to gel by small amounts of borax. | ||||||||||||||||||||||
| Air & Water Reactions | The organic dusts can react violently when suspended in air in the presence of an ignitable source. . Insoluble in water. | ||||||||||||||||||||||
| Reactivity Profile | Guar gum is a ether-alcohol derivative, the ether being relatively unreactive. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert alcohols to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides. | ||||||||||||||||||||||
| Health Hazard | ACUTE/CHRONIC HAZARDS: When heated to decomposition Guar gum emits irritating fumes and smoke. | ||||||||||||||||||||||
| Fire Hazard | Flash point data for Guar gum are not available. However, Guar gum is probably combustible. | ||||||||||||||||||||||
| Pharmaceutical Applications | Guar gum is a galactomannan, commonly used in cosmetics, foodproducts, and pharmaceutical formulations. It has also beeninvestigated in the preparation of sustained-release matrix tabletsin the place of cellulose derivatives such as methylcellulose. In pharmaceuticals, guar gum is used in solid-dosage forms as abinder and disintegrant; in oral and topical productsas a suspending, thickening, and stabilizing agent; and also as acontrolled-release carrier. Guar gum has also been examined for usein colonic drug delivery. Guar-gum-based three-layer matrixtablets have been used experimentally in oral controlled-releaseformulations. Therapeutically, guar gum has been used as part of the diet ofpatients with diabetes mellitus. It has also been used as anappetite suppressant, although its use for this purpose, in tabletform, is now banned in the UK. | ||||||||||||||||||||||
| Biochem/physiol Actions | Guar gum has been shown to have numerous beneficial effects including improved glucose tolerance and attenuation of diabetic nephropathy. | ||||||||||||||||||||||
| Safety | Guar gum is widely used in foods, and oral and topicalpharmaceutical formulations. Excessive consumption may causegastrointestinal disturbance such as flatulence, diarrhea, or nausea.Therapeutically, daily oral doses of up to 25 g of guar gum havebeen administered to patients with diabetes mellitus. Although it is generally regarded as a nontoxic and nonirritantmaterial, the safety of guar gum when used as an appetitesuppressant has been questioned. When consumed, the gum swellsin the stomach to promote a feeling of fullness. However, it isclaimed that premature swelling of guar gum tablets may occur andcause obstruction of, or damage to, the esophagus. Consequently,appetite suppressants containing guar gum in tablet form have beenbanned in the UK. However, appetite suppressants containingmicrogranules of guar gum are claimed to be safe. The use ofguar gum for pharmaceutical purposes is unaffected by the ban. In food applications, an acceptable daily intake of guar gum hasnot been specified by the WHO. LD50 (hamster, oral): 6.0 g/kg LD50 (mouse, oral): 8.1 g/kg LD50 (rabbit, oral): 7.0 g/kg LD50 (rat, oral): 6.77 g/kg | ||||||||||||||||||||||
| storage | Aqueous guar gum dispersions have a buffering action and arestable at pH 4.0–10.5. However, prolonged heating reduces theviscosity of dispersions. The bacteriological stability of guar gum dispersions may beimproved by the addition of a mixture of 0.15% methylparabenand 0.02% propylparaben as a preservative. In food applications,benzoic acid, citric acid, sodium benzoate, or sorbic acid may beused. Guar gum powder should be stored in a well-closed container ina cool, dry place. | ||||||||||||||||||||||
| Properties and Applications |
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| Incompatibilities | Guar gum is compatible with most other plant hydrocolloids suchas tragacanth. It is incompatible with acetone, ethanol (95%),tannins, strong acids, and alkalis. Borate ions, if present in thedispersing water, will prevent the hydration of guar gum. However,the addition of borate ions to hydrated guar gum produces cohesivestructural gels and further hydration is then prevented. The gelformed can be liquefied by reducing the pH to below 7, or byheating. Guar gum may reduce the absorption of penicillin V from someformulations by a quarter. | ||||||||||||||||||||||
| Regulatory Status | GRAS listed. Accepted for use as a food additive in Europe.Included in the FDA Inactive Ingredients Database (oral suspensions,syrups, and tablets; topical preparations; vaginal tablets).Also included in nonparenteral medicines licensed in the UK.Included in the Canadian List of Acceptable Non-medicinalIngredients. |
Guar gum Preparation Products And Raw materials
