H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT CAS 23815-87-4

Introduction：Basic information about H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT CAS 23815-87-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT Basic information

• Product Name: H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT
• Synonyms: H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT;H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACOH;ARG-PRO-PRO-GLY-PHE-SER-PRO;ARG-PRO-PRO-GLY-PHE-SER-PRO ACETATE;BRADYKININ FRAGMENT 1-7;BRADYKININ (1-7);BRADYKININ 1-7 ACETATE;RPPGFSP
• CAS: 23815-87-4
• MF: C35H52N10O9
• MW: 756.85
• Product Categories: Peptide;Bradykinins;Peptides and Proteins;Peptides for Cell Biology
• Mol File: 23815-87-4.mol

H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT Chemical Properties

• storage temp.: −20°C
• solubility: Soluble in DMSO
• form: Powder
• color: White to off-white
• Water Solubility: Soluble in water (1 mg/ml).
• Sequence: Arg-Pro-Pro-Gly-Phe-Ser-Pro
• InChIKey: CRROPKNGCGVIOG-UHFFFAOYSA-N
• SMILES: NC(CCCNC(N)=N)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)NCC(=O)NC(Cc3ccccc3)C(=O)NC(CO)C(=O)N4CCCC4C(O)=O

Safety Information

• WGK Germany: 3
• Storage Class: 11 - Combustible Solids

H-ARG-PRO-PRO-GLY-PHE-SER-PRO-OH ACETATE SALT Usage And Synthesis

Uses

Bradykinin Fragment 1-7 is used in research on the specificity and kinetics of kininase(s). Bradykinin dilates blood vessels via the release of prostacyclin, nitric oxide, and Endothelium Derived Hyperpolarizing Factor. Bradykinin is a physiologically and pharmacologically active peptide of the kinin group of proteins, consisting of nine amino acids.

Definition

ChEBI: [des-Phe(8), des-Arg(9)]-bradykinin is a seven-membered oligopeptide comprising Arg, Pro, Pro, Gly, Phe, Ser, and Pro residues joined in sequence by peptide bonds. It is a metabolite of bradykinin lacking the Phe residue at position 8 and the Arg residue at position 9. It has a role as a human metabolite and a rat metabolite. It is a conjugate base of a [des-Phe(8), des-Arg(9)]-bradykinin(1+).

Biological Activity

Bradykinin (BK) is a pro-inflammatory mediator and a neuromediator. It modulates several vascular and renal functions. Bradykinin (BK) plays a key role in inducing vascular permeability and mitogenesis. It helps to activate the liberation of nitric oxide in inflammatory and cancer tissues.