Hexadecyl trimethyl ammonium bromide CAS 57-09-0
Introduction：Basic information about Hexadecyl trimethyl ammonium bromide CAS 57-09-0, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Hexadecyl trimethyl ammonium bromide Basic information
| Product Name: | Hexadecyl trimethyl ammonium bromide |
| Synonyms: | N-CETYL-N,N,N-TRIMETHYLAMMONIUM BROMIDE;N,N,N-TRIMETHYLTETRADECYLAMMONIUM BROMIDE;N-HEXADECYL-N,N,N-TRIMETHYLAMMONIUM BROMIDE;N-HEXADECYLTRIMETHYLAMMONIUM BROMIDE;PALMITYLTRIMETHYLAMMONIUM BROMIDE;TIMTEC-BB SBB008910;TRIMETHYLHEXADECYL-AMMONIUM BROMIDE;1-Hexadecanaminium,N,N,N-trimethyl-,bromide |
| CAS: | 57-09-0 |
| MF: | C19H42BrN |
| MW: | 364.45 |
| EINECS: | 200-311-3 |
| Product Categories: | CETAB;Pharmaceutical raw materials;Ammonium Bromides (Quaternary);Biochemistry;Cationic Surfactants (for Biochemistry);Quaternary Ammonium Compounds;Surfactants (for Biochemistry);Organics;bc0001;57-09-0 |
| Mol File: | 57-09-0.mol |
Hexadecyl trimethyl ammonium bromide Chemical Properties
| Melting point | 248-251 °C(lit.) |
| density | 1.1107 (rough estimate) |
| bulk density | 390kg/m3 |
| refractive index | 1.5260 (estimate) |
| Fp | 244 °C |
| storage temp. | Store below +30°C. |
| solubility | H2O: 50 mg/mL |
| form | powder |
| color | white |
| PH | 5.0-7.0 (25℃, 0.1M in H2O) |
| Odor | Odorless |
| PH Range | 5 - 7 |
| Water Solubility | 13 g/L (20 ºC) |
| Sensitive | Hygroscopic |
| λmax | λ: 260 nm Amax: 0.06 λ: 280 nm Amax: 0.05 |
| Merck | 14,2025 |
| BRN | 3598189 |
| Stability: | Stable. Incompatible with strong oxidizing agents. Protect from moisture. |
| Cosmetics Ingredients Functions | PRESERVATIVE ANTISTATIC SURFACTANT - EMULSIFYING ANTIMICROBIAL |
| Cosmetic Ingredient Review (CIR) | Hexadecyl trimethyl ammonium bromide (57-09-0) |
| InChI | 1S/C19H42N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(2,3)4;/h5-19H2,1-4H3;1H/q+1;/p-1 |
| InChIKey | LZZYPRNAOMGNLH-UHFFFAOYSA-M |
| SMILES | [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C |
| CAS DataBase Reference | 57-09-0(CAS DataBase Reference) |
| EPA Substance Registry System | Cetyl trimethyl ammonium bromide (57-09-0) |
Safety Information
| Hazard Codes | Xn,N |
| Risk Statements | 22-37/38-41-50-50/53-36/37/38-48/22 |
| Safety Statements | 26-39-61-37/39-60-36 |
| RIDADR | UN 3077 9/PG 3 |
| WGK Germany | 3 |
| RTECS | BQ7875000 |
| F | 3 |
| TSCA | TSCA listed |
| HazardClass | 9 |
| PackingGroup | III |
| HS Code | 29239000 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 1 Eye Dam. 1 Skin Irrit. 2 STOT RE 2 Oral STOT SE 3 |
| Toxicity | LD50 in mice, rats (mg/kg): 32.0, 44.0 i.v. (Isomaa, Bjondahl) |
| Chemical Properties | White powder. Soluble in water, alcohol,and chloroform. |
| Uses | Hexadecyltrimethylammonium Bromide (CTAB) is a cationic surfactant used as a template in the synthesis of Mesoporous γ-Fe2O3. |
| Uses | cetrimonium bromide is a quaternary ammonium salt that can prevent the proliferation of bacteria, fungi, and yeast in cosmetic preparation, while also act as an emulsifying agent. |
| Uses | antiinfectant |
| Uses | A cationic detergent used in the isolation of high molecular weight DNA. |
| Definition | ChEBI: The organic bromide salt that is the bromide salt of cetyltrimethylammonium; one of the components of the topical antiseptic cetrimide. |
| General Description | Hexadecyltrimethylammonium bromide is a titrant for the potentiometric titration of perchlorate with ionselective electrodes. |
| Biochem/physiol Actions | Hexadecyltrimethylammonium bromide also called cetyltrimethylammonium bromide (CTAB), is a cationic surfactant. CTAB is employed for extraction of DNA. CTAB method is efficient, cost and time effective for DNA extraction. CTAB is used as a shaping material and reducing agent for nanoparticle generation. |
| Purification Methods | Crystallise it from EtOH, EtOH/*benzene or from wet acetone after extracting twice with pet ether. Shake it with anhydrous diethyl ether, filter and dissolve it in a little hot MeOH. After cooling in the refrigerator, the precipitate is filtered off at room temperature and re-dissolved in MeOH. Anhydrous ether is added and, after warming to obtain a clear solution, it is cooled and the crystalline material is collected. [Dearden & Wooley J Phys Chem 91 2404 1987, Hakemi et al. J Am Chem Soc 91 120 1987, Beilstein 4 IV 819.] |
| References | [1] Liu, Tingting et al. “Hexadecyl trimethyl ammonium bromide assisted growth of NiCo2O4@reduced graphene oxide/ nickel foam nanoneedle arrays with enhanced performance for supercapacitor electrodes?.” RSC Advances 7 (2022): 4029–4041. |
Hexadecyl trimethyl ammonium bromide Preparation Products And Raw materials
| Raw materials | Bromine-->Trimethylamine-->1-Hexadecanol-->1-Bromohexadecane-->1-amino-2-propanone-->Hexadecyldimethylamine |
| Preparation Products | 1-(N-METHYLPIPERIDIN-3-YL-METHYL)PIPERAZINE-->Diphenylacetylene-->Fluazifop-P-butyl-->1-PYRIDIN-3-YLMETHYL-PIPERAZINE-->3-CYANO-7-METHOXYCOUMARIN-->the chelating resin of crosslinking chitosan condense with salilylaldehyde-->1，3，6，8-Tetranitronaphthalene-->AMINOPEPTIDASE M-->Methyl Orange-->Sodium cyanide-->4-CHLOROMETHYLPHENYLACETIC ACID METHYL ESTER-->Hexadecyl trimethyl ammonium iodide |
