Hexamethylphosphorous triamide CAS 1608-26-0
Introduction：Basic information about Hexamethylphosphorous triamide CAS 1608-26-0, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Hexamethylphosphorous triamide Basic information
| Product Name: | Hexamethylphosphorous triamide |
| Synonyms: | Hexamethylphosphorous triamide ,98％;HEXAMETHYLTRIAMINOPHOSPHINE;HEXAMETHYL PHOSPHORUS TRIAMIDE;HEXAMETHYLPHOSPHOROUS TRIAMIDE;HMPT;Trisdimethylaminophosphorus;HEXAMETHYLPHOSPHOROUS TRIAMIDE, 97 %;Tri(dimethylamino)phosphine |
| CAS: | 1608-26-0 |
| MF: | C6H18N3P |
| MW: | 163.2 |
| EINECS: | 216-534-4 |
| Product Categories: | organophosphorus ligand;Miscellaneous Reagents;Phosphorylating and Phosphitylating Agents |
| Mol File: | 1608-26-0.mol |
Hexamethylphosphorous triamide Chemical Properties
| Melting point | -44 °C |
| Boiling point | 48-50 °C/12 mmHg (lit.) |
| density | 0.898 g/mL at 25 °C (lit.) |
| refractive index | n |
| Fp | 73 °F |
| storage temp. | Inert atmosphere,2-8°C |
| form | Liquid |
| pka | 8.03±0.70(Predicted) |
| color | Clear colorless to slightly yellow |
| Specific Gravity | 0.8980 |
| Water Solubility | REACTS |
| Sensitive | Moisture Sensitive |
| BRN | 906778 |
| Stability: | Stable. Highly flammable - note low flash point. Incompatible with oxidizing agents. |
| InChI | 1S/C6H18N3P/c1-7(2)10(8(3)4)9(5)6/h1-6H3 |
| InChIKey | XVDBWWRIXBMVJV-UHFFFAOYSA-N |
| SMILES | CN(C)P(N(C)C)N(C)C |
| CAS DataBase Reference | 1608-26-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Phosphorous triamide, hexamethyl-(1608-26-0) |
| EPA Substance Registry System | Phosphorous triamide, hexamethyl- (1608-26-0) |
Safety Information
| Hazard Codes | T,Xi,Xn,F |
| Risk Statements | 45-46-10-40-36/37/38 |
| Safety Statements | 53-45-36/37/39-26-16-37/39-36 |
| RIDADR | UN 1993 3/PG 3 |
| WGK Germany | 3 |
| RTECS | TH3390000 |
| F | 10 |
| Hazard Note | Irritant |
| TSCA | TSCA listed |
| HazardClass | 3 |
| PackingGroup | III |
| HS Code | 29299000 |
| Storage Class | 3 - Flammable liquids |
| Hazard Classifications | Carc. 1B Eye Irrit. 2 Flam. Liq. 3 Muta. 1B Skin Irrit. 2 |
| Chemical Properties | colourless liquid |
| Uses | Hexamethylphosphorous triamide can be widely used in industry, with applications such as being a flame retardant for building materials to a phosphorylating agent in synthetic chemistry. It is a classified carcinogen. |
| Uses | Hexamethylphosphorous triamide can be uesd in suzuki reaction. |
| Uses | Hexamethylphosphorous triamide can be combination with CCl4 for the conversion of hydroxyl groups to the corresponding chlorides; hydroxyl group activation; dehydrations. |
| reaction suitability | reagent type: ligand reaction type: Reductions reagent type: ligand reaction type: Suzuki-Miyaura Coupling reagent type: ligand reaction type: Wittig Reaction |
| Purification Methods | It may contain more than 1% of phosphoric triamide. The yellow oil is first distilled at atmospheric pressure, then under reduced pressure and stored under N2. It is air sensitive, TOXIC, and should not be inhaled. It is absorbed through the skin. [Mark Org Synth Coll Vol V 602 1973, Beilstein 4 IV 274.] |
Hexamethylphosphorous triamide Preparation Products And Raw materials
| Raw materials | Sodium hydroxide-->Hydrochloric acid-->Diethyl ether-->Tetrahydrofuran-->Hexane-->Lithium Aluminum Hydride-->Phosphorus trichloride-->Dimethylamine-->Cyclohexane-->N,N-Dimethyltrimethylsilylamine |
| Preparation Products | (11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-DIMETHYLAMINE-->(11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-DIMETHYLAMINE-->DIMEFOX-->N,N-DIMETHYLHEXANAMIDE-->DIMETHYLPHOSPHORAMIDOUS DICHLORIDE-->1,1-DIMETHYLUREA |
