Introduction：Basic information about HOOCCH2CH2O-PEG10-CH2CH2COOH CAS 2097010-30-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
HOOCCH2CH2O-PEG10-CH2CH2COOH Basic information
| Product Name: | HOOCCH2CH2O-PEG10-CH2CH2COOH |
| Synonyms: | HOOCCH2CH2O-PEG10-CH2CH2COOH;HOOCCH2CH2-PEG10-CH2CH2COOH;4,7,10,13,16,19,22,25,28,31,34-Undecaoxaheptatriacontanedioic acid;Di-Acid-PEG11;HOOCCH2CH2O-PEG10-CH2CH2COOH/4,7,10,13,16,19,22,25,28,31,34-undecaoxaheptatriacontane-1,37-dioic acid |
| CAS: | 2097010-30-3 |
| MF: | C26H50O15 |
| MW: | 602.67 |
| EINECS: | |
| Product Categories: | peg |
| Mol File: | 2097010-30-3.mol |
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HOOCCH2CH2O-PEG10-CH2CH2COOH Chemical Properties
| Boiling point | 684.6±55.0 °C(Predicted) |
| density | 1.165±0.06 g/cm3(Predicted) |
| pka | 3.97±0.10(Predicted) |
Safety Information
HOOCCH2CH2O-PEG10-CH2CH2COOH Usage And Synthesis
| Uses | Bis-PEG11-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Biological Activity | Bis-PEG11-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| IC 50 | PEGs |
| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
HOOCCH2CH2O-PEG10-CH2CH2COOH Preparation Products And Raw materials
