HYDROXYCALABAXANTHONE, 9- CAS 35349-68-9

Introduction：Basic information about HYDROXYCALABAXANTHONE, 9- CAS 35349-68-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

HYDROXYCALABAXANTHONE, 9- Basic information

• Product Name: HYDROXYCALABAXANTHONE, 9-
• Synonyms: 9-HYDROXYCALABAXANTHONE;HYDROXYCALABAXANTHONE, 9-;1,6-Dihydroxy-7-methoxy-8-(3-methylbut-2-enyl)-6',6'-dimethylpyrano(2',3':3,2)xanthone;Xanthone I;5,9-Dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-buten-1-yl)-2H,6H-pyrano[3,2-b]xanthen-6-one;2H,6H-Pyrano[3,2-b]xanthen-6-one, 5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-buten-1-yl)-;5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methylbut-2-enyl)pyrano[3,2-b]xanthen-6-one;5,9-Dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methylbut-2-en-1-yl)pyrano[3,2-b]xanthen-6(2H)-one
• CAS: 35349-68-9
• MF: C24H24O6
• MW: 408.44
• Mol File: 35349-68-9.mol

HYDROXYCALABAXANTHONE, 9- Chemical Properties

• Melting point: 155-157 °C
• Boiling point: 617.6±55.0 °C(Predicted)
• density: 1.277±0.06 g/cm3(Predicted)
• storage temp.: 4°C, protect from light
• pka: 6.46±0.40(Predicted)
• form: Solid
• color: Yellow to brown

HYDROXYCALABAXANTHONE, 9- Usage And Synthesis

Uses

9-Hydroxycalabaxanthone (Xanthone I) is a known xanthone isolated from Garcinia mangostana Linn. 9-Hydroxycalabaxanthone has quorum-sensing inhibitory, anti-microbial, and anti-malarial activities (IC50=1.2-1.5 μM)[1].

Definition

ChEBI: 9-Hydroxycalabaxanthone is a member of xanthones.

IC 50

Plasmodium

References

[1] Gamal A Mohamed, et al. Mangostanaxanthones I and II, New Xanthones From the Pericarp of Garcinia Mangostana. Fitoterapia. 2014 Oct;98:215-21. DOI:10.1016/j.fitote.2014.08.014
[2] Wanna Chaijaroenkul,? et al. The in Vitro Antimalarial Interaction of 9-hydroxycalabaxanthone and α-mangostin With mefloquine/artesunate. Acta Parasitol.?2014 Mar;60(1):105-11. DOI:10.1515/ap-2015-0013