Indocyanine green CAS 3599-32-4
Introduction：Basic information about Indocyanine green CAS 3599-32-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Indocyanine green Basic information
| Product Name: | Indocyanine green |
| Synonyms: | UJOVIRIDIN;Foxgreen, IC Green, Indocyanine green;Cardiogreen, Foxgreen, IR-125;1H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrien-1-yl]-1,1-dimethyl-3-(4-sulfobutyl)-, inner salt, sodium salt (1:1);3-dimethyl-1-(4-sulfonatobutyl)benz(e)indolin-2-ylidene)hepta-1;3-dimethyl-1-(4-sulfonatobutyl)benz[e]indolinium;5-trien-1-yl)-3;Sodium 2-(7-(3 |
| CAS: | 3599-32-4 |
| MF: | C43H49N2NaO6S2 |
| MW: | 776.98 |
| EINECS: | 222-751-5 |
| Product Categories: | Cyanine Dyes;Fluorescent Labels & Indicators;Sulfur & Selenium Compounds |
| Mol File: | 3599-32-4.mol |
Indocyanine green Chemical Properties
| Melting point | 235 °C |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | H2O: soluble1mg/mL |
| form | Powder |
| color | Green-bronze |
| Appearance | Dark green solid |
| Water Solubility | slightly soluble |
| ex/em | 786/820nm (Methanol) |
| Φ(quantum yield) | 0.09 |
| ε(extinction coefficient) | ≥115 at 386-396nm in water ≥2000 at 774-784nm in water ≥900 at 712-722nm in water |
| Merck | 14,4962 |
| BRN | 4115884 |
| Major Application | diagnostic assay manufacturing hematology histology |
| Cosmetics Ingredients Functions | UV ABSORBER |
| InChIKey | JDDBTPDPBRYGPQ-UHFFFAOYSA-N |
| SMILES | CC1(C(=[N+](CCCCS([O-])(=O)=O)C2C=CC3=CC=CC=C3C1=2)C=CC=CC=CC=C1C(C2C3=CC=CC=C3C=CC=2N1CCCCS(O)(=O)=O)(C)C)C.[NaH] |
| LogP | -0.290 |
| CAS DataBase Reference | 3599-32-4(CAS DataBase Reference) |
| EPA Substance Registry System | 1H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-, inner salt, sodium salt (3599-32-4) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-37/39 |
| WGK Germany | 3 |
| RTECS | DE3150000 |
| TSCA | TSCA listed |
| HS Code | 32129000 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
| Hazardous Substances Data | 3599-32-4(Hazardous Substances Data) |
| Toxicity | LD50 intravenous in mouse: 60mg/kg |
| Description | Indocyanine Green (aka ICG, IC Green, Foxgreen) is used for reliable imaging and flow cytometry. This dye is water-soluble and pH-insensitive. The fluorescence of Indocyanine Green is not visible to the human eye but is readily detected by most imaging systems. Indocyanine Green binds tightly to plasma proteins and becomes confined to the vascular system. The dye has a half-life of 150 to 180 sec and is removed from circulation exclusively by the liver to bile juice. Indocyanine Green is used for detection of hepatocyte-like cells, determining cardiac output, hepatic function, liver and gastric blood flow, and for ophthalmic angiography. |
| Chemical Properties | green to brown crystals or crystalline powder |
| Uses | In infrared photography; in preparation of Wratten filters. |
| Uses | A tricarbocyanine type of dye with infrared absorbing properties. Diagnostic aid (blood volume determination, cardiac output, hepatic function). Dyes and metabolites. |
| Brand name | IC-Green(Akorn). |
| Safety Profile | Poison by intravenous route. When heated to decomposition it emits very toxic fumes of SOx, Na2O, and NOx. |
| storage | Store at -20°C |
| Abs/Em Maxima | 787/819 nm |
| Fluoresene quantum yield | 0.09 |
| Extinction Coefficient | 232000 |
Indocyanine green Preparation Products And Raw materials
