Introduction：Basic information about Iriflophene CAS 52591-10-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Iriflophene Basic information
| Product Name: | Iriflophene |
| Synonyms: | Iriflophene;Methanone, (4-hydroxyphenyl)(2,4,6-trihydroxyphenyl)-;Iriflophenone;4,2',4',6'-tetrahydroxybenzophenon;(4-Hydroxyphenyl)(2,4,6-trihydroxyphenyl)methanone;Iriflophene/4,2',4',6'-tetrahydroxybenzophenon;Inhibitor,MCF-7,proliferation,Iriflophenone,cells,T-47D,inhibit;Iriflophenone, 10 mM in DMSO |
| CAS: | 52591-10-3 |
| MF: | C13H10O5 |
| MW: | 246.22 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 52591-10-3.mol |
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Iriflophene Chemical Properties
| Melting point | 210 °C |
| Boiling point | 482.4±33.0 °C(Predicted) |
| density | 1.526±0.06 g/cm3(Predicted) |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | powder |
| pka | 7.03±0.40(Predicted) |
| color | Yellow |
Safety Information
Iriflophene Usage And Synthesis
| Uses | Iriflophenone, isolated from Aquilaria sinensis, stimulates MCF-7 and T-47D human breast cancer cells proliferation[1][2]. |
| Preparation | Preparation by reaction of p-hydroxybenzonitrile with phloroglucinol, (15%) (Hoesch reaction). |
| target | Estrogen receptor | Progestogen receptor |
| References | [1] Monthakantirat O, et al. Phenolic constituents of the rhizomes of the Thai medicinal plant Belamcanda chinensis with proliferative activity for two breast cancer cell lines. J Nat Prod. 2005;68(3):361-364. DOI:10.1021/np040175c
[2] Kumar V, et al. Detection of intermediates through high-resolution mass spectrometry for constructing biosynthetic pathways for major chemical constituents in a medicinally important herb, Swertia chirayita. Nat Prod Res. 2015;29(15):1449-1455. DOI:10.1080/14786419.2015.1004175 |
Iriflophene Preparation Products And Raw materials
